Gene: RAD9B
Official Full Name: RAD9 checkpoint clamp component Bprovided by HGNC
Gene Summary: Predicted to be involved in DNA integrity checkpoint signaling; DNA repair; and cellular response to ionizing radiation. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24089 | RAD9B Knockout cell line (HeLa) | Human | RAD9B | 1:3~1:6 | Negative | Online Inquiry |
RAD9B Gene Knockout Cell Lines are custom-engineered human cell lines that have been genetically modified to disrupt the RAD9B gene, which plays a critical role in the DNA damage response and cell cycle regulation. By employing advanced CRISPR/Cas9 technology, these knockout cell lines offer a powerful tool for studying the biological functions of the RAD9B gene and its implications in various cellular processes, including tumorigenesis and genomic stability.
The primary mechanism of action involves the gene editing of RAD9B, resulting in the abrogation of its normal function. This allows for the investigation of downstream effects on cellular pathways involved in repair mechanisms and response to genotoxic stress. Researchers can utilize these knockout cell lines to elucidate the role of RAD9B in cancer biology, assess drug sensitivity, and evaluate potential therapeutic targets.
The scientific importance of RAD9B Gene Knockout Cell Lines is underscored by their utility in both basic and applied research settings. They serve as invaluable models for understanding diseases linked to impaired DNA repair pathways, providing insights that are critical for developing novel cancer therapies. Additionally, their application in high-throughput screening assays enhances their relevance in pharmacological research.
What sets RAD9B Gene Knockout Cell Lines apart from alternative products is their precise genetic modification and robust characterization, ensuring reproducibility and reliability in experimental outcomes. Unlike other models, these cell lines are optimized for a wide range of studies, from mechanistic investigations to drug development.
Researchers and clinicians stand to benefit significantly from integrating RAD9B Gene Knockout Cell Lines into their work, as these models not only streamline experimental processes but also enhance the accuracy of findings related to DNA repair mechanisms. This can ultimately lead to advances in personalized medicine and targeted therapies.
With a commitment to excellence in genetic engineering and a deep understanding of cellular biology, our company is dedicated to providing cutting-edge biological tools that empower researchers in their quest for innovation and discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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