Gene: RAC2
Official Full Name: Rac family small GTPase 2provided by HGNC
Gene Summary: This gene encodes a member of the Ras superfamily of small guanosine triphosphate (GTP)-metabolizing proteins. The encoded protein localizes to the plasma membrane, where it regulates diverse processes, such as secretion, phagocytosis, and cell polarization. Activity of this protein is also involved in the generation of reactive oxygen species. Mutations in this gene are associated with neutrophil immunodeficiency syndrome. There is a pseudogene for this gene on chromosome 6. [provided by RefSeq, Jul 2013]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO10529 | RAC2 Knockout cell line (HeLa) | Human | RAC2 | 1:3~1:6 | Negative | Online Inquiry |
KO10530 | RAC2 Knockout cell line (HCT 116) | Human | RAC2 | 1:2~1:4 | Negative | Online Inquiry |
RAC2 Gene Knockout Cell Lines are genetically modified cell lines in which the RAC2 gene has been specifically disrupted. The RAC2 gene encodes a member of the Rho family of small GTPases, which play crucial roles in signaling pathways that regulate cellular processes such as growth, cytoskeletal dynamics, and immune function. By employing advanced CRISPR/Cas9 gene-editing technology, these cell lines enable researchers to study the impact of RAC2 deficiency on a variety of cellular behaviors and signaling pathways, providing insights into its role in both normal physiology and disease contexts.
The key function of these knockout cell lines is to serve as an invaluable tool for elucidating the biological functions of RAC2, particularly in the contexts of hematopoiesis, cell migration, and immune responses. By studying the effects of RAC2 deletion, scientists can investigate its involvement in various pathologies, such as immunodeficiency disorders and cancers, potentially leading to the identification of novel therapeutic targets.
In research and clinical settings, the importance of RAC2 Gene Knockout Cells is underscored by their applicability in drug development, disease modeling, and functional genomics. These cell lines allow for precise manipulation of the RAC2-related signaling pathways, making them essential for studying the molecular mechanisms underlying immune system dysregulation and tumor progression.
One major advantage of RAC2 Gene Knockout Cell Lines is their consistency and reproducibility, especially when compared to other methods of gene disruption, such as RNA interference or traditional knockout strategies. The CRISPR/Cas9 technology used assures a high efficiency of gene editing, drastically reducing the risk of off-target effects and generating stable, clonal populations that can be relied upon for high-quality experimental results.
For researchers and clinicians, the value of these cell lines lies in their enhanced ability to dissect complex biological processes and identify new therapeutic avenues. These tools empower the scientific community, offering a platform for groundbreaking discoveries and advancements in cancer research, autoimmune diseases, and beyond.
Our company prides itself on delivering high-quality, precision-based biological products, ensuring that our clients have access to state-of-the-art research tools that foster innovation and scientific progress. With extensive expertise in molecular biology and genetics, we are committed to supporting researchers in achieving their goals through the use of advanced products like RAC2 Gene Knockout Cell Lines.
Please note that all services are for research use only. Not intended for any clinical use.
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