Gene: RAB37
Official Full Name: RAB37, member RAS oncogene familyprovided by HGNC
Gene Summary: Rab proteins are low molecular mass GTPases that are critical regulators of vesicle trafficking. For additional background information on Rab proteins, see MIM 179508.[supplied by OMIM, Apr 2006]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO14747 | RAB37 Knockout cell line (HCT 116) | Human | RAB37 | 1:2~1:4 | Negative | Online Inquiry |
KO14748 | RAB37 Knockout cell line (A549) | Human | RAB37 | 1:3~1:4 | Negative | Online Inquiry |
RAB37 Gene Knockout Cell Lines represent a powerful tool engineered for the study of RAB37 function in cellular processes and its implications in various pathological conditions. These cell lines have been created through targeted genome editing techniques, specifically utilizing CRISPR-Cas9 technology, which ensures precise disruption of the RAB37 gene, allowing researchers to investigate the gene's roles and interactions within cellular pathways.
The primary function of RAB37 involves its regulation of vesicle trafficking, which is critical for maintaining cellular homeostasis and facilitating communication between cellular compartments. By utilizing RAB37 knockout cell lines, scientists can elucidate the consequences of RAB37 deficiency on intracellular transport mechanisms, exocytosis, and endocytosis, thereby contributing to a better understanding of associated diseases such as cancer and neurodegeneration.
The scientific importance of RAB37 Gene Knockout Cell Lines emerges from their broad applications in basic research, drug discovery, and translational medicine. Researchers can utilize these models to explore gene function, validate target pathways in therapy development, and screen for new pharmacological agents that can modulate RAB37-related processes.
Distinctively, RAB37 Gene Knockout Cell Lines provide advantages over traditional approaches, such as transient knockdown techniques, by enabling stable, long-term suppression of the target gene. This stability fosters reproducibility in experimental results and allows for more accurate assessment of phenotypic changes over time. Furthermore, these cell lines are prepared under stringent quality control measures, ensuring high viability and consistent performance across experiments.
For researchers and clinicians alike, the ability to study RAB37-deficient cellular contexts opens potential avenues for therapeutic intervention, steering investigations toward innovative solutions for previously intractable diseases. The integration of this advanced model into lab settings not only streamlines research workflows but also enhances the potential for groundbreaking discoveries.
Our company prides itself on its specialization in developing high-quality genetic modification tools that empower scientific advancement, underscoring our commitment to supporting the research community with cutting-edge biological products, including RAB37 Gene Knockout Cell Lines.
Please note that all services are for research use only. Not intended for any clinical use.
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