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RAB11FIP3 Knockout Cell Lines

Gene: RAB11FIP3

Official Full Name: RAB11 family interacting protein 3provided by HGNC

Gene Summary: Proteins of the large Rab GTPase family (see RAB1A; MIM 179508) have regulatory roles in the formation, targeting, and fusion of intracellular transport vesicles. RAB11FIP3 is one of many proteins that interact with and regulate Rab GTPases (Hales et al., 2001 [PubMed 11495908]).[supplied by OMIM, Mar 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32861 RAB11FIP3 Knockout cell line (HeLa) Human RAB11FIP3 1:3~1:6 Negative Online Inquiry
KO32862 RAB11FIP3 Knockout cell line (HCT 116) Human RAB11FIP3 1:2~1:4 Negative Online Inquiry
KO32863 RAB11FIP3 Knockout cell line (HEK293) Human RAB11FIP3 1:3~1:6 Negative Online Inquiry
KO32864 RAB11FIP3 Knockout cell line (A549) Human RAB11FIP3 1:3~1:4 Negative Online Inquiry

Background

RAB11FIP3 Gene Knockout Cell Lines are genetically engineered cell lines wherein the RAB11FIP3 gene has been functionally disrupted. RAB11FIP3 plays a crucial role in intracellular transport processes, particularly in the recycling of membrane proteins and the regulation of exocytosis. The knockout of this gene provides researchers with a powerful tool to dissect the underlying biological functions of RAB11FIP3 in cellular contexts, offering insights into cellular trafficking and signaling pathways.

These cell lines operate under the principle of gene editing, typically utilizing CRISPR-Cas9 technology to create specific mutations that result in the loss of RAB11FIP3 protein expression. This functional absence allows for the study of the wide-ranging effects on cellular morphology, receptor recycling, and protein transport mechanisms, providing a pivotal model for research into diseases where these processes are significantly disrupted, such as cancer and neurodegenerative disorders.

In terms of scientific importance, RAB11FIP3 Gene Knockout Cell Lines are invaluable in both basic and applied research settings. They enable investigators to explore the molecular underpinnings of cellular dysfunction, elucidate the effects of pharmacological interventions on trafficking pathways, and contribute to the development of targeted therapies. This product stands out in the market due to its reliable gene knockout efficiency and consistent performance in a variety of experimental conditions.

One of the key advantages of using RAB11FIP3 Gene Knockout Cell Lines is their compatibility with high-throughput screening applications, aiding in the identification of novel compounds that may restore normal trafficking in pathophysiological contexts. Moreover, these cell lines are readily available and characterized, saving researchers time and resources that would otherwise be spent on generating their own knockout models.

Researchers and clinicians increasingly rely on these cell lines to foster new insights into cellular behaviors that are critical for disease progression and treatment development. With years of expertise in genetic engineering and a commitment to providing high-quality biological products, our company is dedicated to supporting the scientific community in advancing their research objectives through reliable and innovative tools like RAB11FIP3 Gene Knockout Cell Lines.

Please note that all services are for research use only. Not intended for any clinical use.

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