Gene: QSOX2
Official Full Name: quiescin sulfhydryl oxidase 2provided by HGNC
Gene Summary: QSOX2 is a member of the sulfhydryl oxidase/quiescin-6 (Q6) family (QSOX1; MIM 603120) that regulates the sensitization of neuroblastoma cells for IFN-gamma (IFNG; MIM 147570)-induced cell death (Wittke et al., 2003 [PubMed 14633699]).[supplied by OMIM, Jun 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO14759 | QSOX2 Knockout cell line (HeLa) | Human | QSOX2 | 1:3~1:6 | Negative | Online Inquiry |
KO14760 | QSOX2 Knockout cell line (HCT 116) | Human | QSOX2 | 1:2~1:4 | Negative | Online Inquiry |
KO14761 | QSOX2 Knockout cell line (HEK293) | Human | QSOX2 | 1:3~1:6 | Negative | Online Inquiry |
KO14762 | QSOX2 Knockout cell line (A549) | Human | QSOX2 | 1:3~1:4 | Negative | Online Inquiry |
QSOX2 Gene Knockout Cell Lines are genetically engineered cell lines in which the QSOX2 gene has been selectively disrupted. This innovative product serves as a powerful tool for researchers studying the role of QSOX2 in various biological processes, including cell differentiation, proliferation, and oxidative stress response. By providing a model in which the effects of QSOX2 absence can be readily observed, these cell lines facilitate investigations into the gene’s function and its implications in disease states, particularly in cancer and neurodegenerative disorders.
The mechanism by which QSOX2 affects cellular behavior is through its role in thiol-based redox regulation, influencing protein folding and cellular homeostasis. By utilizing CRISPR/Cas9 technology for the knockout process, these cell lines offer a precise modification of the genome, ensuring that researchers can study the downstream effects of QSOX2 disruption with high fidelity. The QSOX2 knockout allows for the identification of signaling pathways and interactions that could be critical for therapeutic target discovery.
In research and clinical settings, the importance of QSOX2 Gene Knockout Cell Lines lies in their ability to unveil the complexities of cellular responses in conditions where this gene is implicated. Experiments employing these cell lines provide insights that can lead to potential biomarker development or novel treatment strategies, thus accelerating scientific understanding and progress.
Compared to alternative models, including RNA interference or pharmacological inhibitors, knockout cell lines offer a permanent and stable genetic alteration, eliminating transient effects that may mislead experimental outcomes. Additionally, these models enable more reproducible results, providing a dependable platform for robust data collection and analysis.
For researchers and clinicians focused on gene function and disease mechanisms, the QSOX2 Gene Knockout Cell Lines represent an invaluable resource. Their use can advance the field of molecular biology and pave the way for innovative therapies, underscoring their relevance in contemporary biomedical research.
With a commitment to producing high-quality biological products, our company has established itself as a leader in the field, providing reliable tools and resources that empower scientists in their quest for knowledge and therapeutic advancements.
Please note that all services are for research use only. Not intended for any clinical use.
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