Gene: PTDSS2
Official Full Name: phosphatidylserine synthase 2provided by HGNC
Gene Summary: The protein encoded by this gene catalyzes the conversion of phosphatidylethanolamine to phosphatidylserine, a structural membrane phospholipid that functions in cell signaling, blood coagulation, and apoptosis. The encoded enzyme also has a high affinity for docosahexaenoic acid (DHA) and can use it to make DHA-containing phosphatidylserine. [provided by RefSeq, Jul 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO05802 | PTDSS2 Knockout cell line (HeLa) | Human | PTDSS2 | 1:3~1:6 | Negative | Online Inquiry |
KO05803 | PTDSS2 Knockout cell line (HCT 116) | Human | PTDSS2 | 1:2~1:4 | Negative | Online Inquiry |
KO05804 | PTDSS2 Knockout cell line (HEK293) | Human | PTDSS2 | 1:3~1:6 | Negative | Online Inquiry |
KO05805 | PTDSS2 Knockout cell line (A549) | Human | PTDSS2 | 1:3~1:4 | Negative | Online Inquiry |
PTDSS2 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the PTDSS2 gene, which encodes a crucial enzyme involved in the synthesis of phosphatidylserine. This product provides researchers with a powerful tool for studying the functional role of PTDSS2 in various biological processes, including cell signaling, apoptosis, and cellular membrane dynamics. The knockout methodology, utilizing CRISPR-Cas9 technology or homologous recombination, ensures precise genetic modifications, allowing for the investigation of genotypic and phenotypic changes associated with the loss of this gene.
The primary function of these cell lines is to facilitate advanced research into the biochemical pathways involving phosphatidylserine, particularly its implications in neurodegenerative diseases, cancer progression, and metabolic disorders. By analyzing the cellular behavior of PTDSS2 knockout lines, scientists can explore the impact of phosphatidylserine deficiency on cellular signaling and inflammation, yielding insights that are pivotal for therapeutic development.
These cell lines hold significant scientific importance in both basic and translational research settings. They offer a unique model for evaluating drug responses and genetic interactions relevant to diseases linked to membrane lipid metabolism. Moreover, PTDSS2 Gene Knockout Cell Lines present advantages over traditional models that may not accurately reflect the complexities of gene function in a human context, thereby providing more reliable and reproducible results.
In addition to their research utility, these cell lines offer advantages such as high genetic stability and adaptability to various culture conditions, making them an indispensable resource for laboratories focusing on lipid biochemistry and disease modeling. By integrating these knockout models into their research arsenal, scientists and clinicians can accelerate the discovery of novel therapeutic interventions, enhance their understanding of diseases, and ultimately contribute to improved patient outcomes.
Our company prides itself on delivering high-quality genetic tools and cell lines, backed by years of expertise in molecular biology and genomics. With a commitment to innovation and scientific advancement, we enable researchers to drive discoveries that can transform lives through enhanced understanding and targeted therapies.
Please note that all services are for research use only. Not intended for any clinical use.
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