Gene: PRSS16
Official Full Name: serine protease 16provided by HGNC
Gene Summary: This gene encodes a serine protease expressed exclusively in the thymus. It is thought to play a role in the alternative antigen presenting pathway used by cortical thymic epithelial cells during the positive selection of T cells. The gene is found in the large histone gene cluster on chromosome 6, near the major histocompatibility complex (MHC) class I region. A second transcript variant has been described, but its full length nature has not been determined. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO32016 | PRSS16 Knockout cell line (HeLa) | Human | PRSS16 | 1:3~1:6 | Negative | Online Inquiry |
KO32017 | PRSS16 Knockout cell line (HCT 116) | Human | PRSS16 | 1:2~1:4 | Negative | Online Inquiry |
KO32018 | PRSS16 Knockout cell line (A549) | Human | PRSS16 | 1:3~1:4 | Negative | Online Inquiry |
PRSS16 Gene Knockout Cell Lines are genetically modified cell lines specifically engineered to lack the expression of the PRSS16 gene, which encodes the serine protease 16 protein. This knockout model serves as a critical tool in elucidating the biological functions of PRSS16, particularly in the context of immune response and cell signaling pathways. By eliminating the gene, researchers can investigate the downstream effects on cellular behavior, enabling a deeper understanding of various physiological and pathological processes.
The key function of these cell lines lies in their ability to facilitate targeted studies regarding the role of serine proteases in biological systems. PRSS16 has been implicated in processes such as immune regulation and inflammation; thus, the knockout model allows for the examination of alterations in immune responses and the cellular mechanisms involved. Researchers utilize these cell lines to assess protein interactions, signaling cascades, and to model disease states in which PRSS16 is deregulated.
In terms of scientific importance, PRSS16 Gene Knockout Cell Lines are invaluable in both research and clinical settings. They provide a means to study autoimmune diseases, cancer progression, and potential therapeutic interventions. Additionally, these cell lines serve as a platform for drug testing, helping to identify compounds that may modulate the activity of serine proteases.
What sets our PRSS16 Gene Knockout Cell Lines apart from alternative products is their comprehensive validation and reproducibility. Each cell line is rigorously characterized, ensuring dependable results across experiments. Moreover, they are compatible with various assays, from high-throughput screening to more intricate functional analyses.
These knockout cell lines offer significant value to researchers and clinicians alike, ameliorating the challenges associated with studying gene function in vivo. By providing a reliable and precise model, they enable a more streamlined approach to experimental design and data interpretation.
Our company is committed to facilitating groundbreaking discoveries through our high-quality biological products. With years of expertise in genetic engineering and cell biology, we deliver innovative solutions that empower the scientific community and enhance the pursuit of research objectives.
Please note that all services are for research use only. Not intended for any clinical use.
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