Gene: PROM2
Official Full Name: prominin 2provided by HGNC
Gene Summary: This gene encodes a member of the prominin family of pentaspan membrane glycoproteins. The encoded protein localizes to basal epithelial cells and may be involved in the organization of plasma membrane microdomains. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO22036 | PROM2 Knockout cell line (HCT 116) | Human | PROM2 | 1:2~1:4 | Negative | Online Inquiry |
PROM2 Gene Knockout Cell Lines are a cutting-edge tool designed for research focused on the PROM2 gene, a critical player in various cellular processes, including proliferation, differentiation, and cell survival mechanisms. By employing CRISPR-Cas9 technology, these cell lines facilitate the targeted disruption of PROM2, rendering researchers the ability to study its role in a variety of physiological and pathological contexts.
The primary mechanism behind PROM2 Gene Knockout Cell Lines lies in their ability to create precise genetic alterations, enabling the complete knockout of the PROM2 gene. This process allows for a detailed investigation into the gene's function in cellular models, by analyzing the resultant phenotypic changes and their implications in disease pathways. Such targeted studies are vital for understanding the underlying mechanisms of conditions like cancer and neurodegenerative disorders, where PROM2 has been implicated.
Scientifically, these knockout cell lines represent a significant advancement in reverse genetics approaches, providing essential models for drug discovery and therapeutic development. Their application extends into both basic and translational research, making them invaluable for institutions seeking to bridge the gap between laboratory findings and clinical applications.
In comparison to alternative cell lines or traditional knockout methods, PROM2 Gene Knockout Cell Lines offer superior specificity and efficiency, reducing the off-target effects often seen with older techniques. This precision ensures that experimental results are both reproducible and reliable, which is paramount in scientific exploration.
For researchers and clinicians, the value of PROM2 Gene Knockout Cell Lines lies in their ability to unlock new insights into gene function and regulation, ultimately leading to the identification of novel therapeutic targets. These cell lines are not only a testament to our commitment to advancing research tools but also reflect our company’s expertise in providing high-quality, innovative biological products tailored to the needs of the scientific community.
Please note that all services are for research use only. Not intended for any clinical use.
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