Gene: POU2AF2
Official Full Name: POU class 2 homeobox associating factor 2provided by HGNC
Gene Summary: Enables sequence-specific DNA binding activity and transcription coactivator activity. Predicted to be involved in positive regulation of DNA-templated transcription. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO14963 | POU2AF2 Knockout cell line (HEK293) | Human | POU2AF2 | 1:3~1:6 | Negative | Online Inquiry |
POU2AF2 Gene Knockout Cell Lines are precisely engineered cellular models designed to study the functional implications of the POU2AF2 gene, which encodes a transcription factor integral to the immune response and B-cell differentiation. By utilizing CRISPR-Cas9 technology, these cell lines provide researchers with a powerful tool to assess the roles of POU2AF2 in various biological processes, including lymphocyte development, antibody production, and immune regulation.
The mechanism underlying these cell lines involves targeted disruption of the POU2AF2 gene, leading to a loss of function that can be systematically analyzed. The consequent phenotypic changes in cellular behavior can reveal insights into transcriptional control, gene expression patterns, and cellular responses to stimuli. This allows for a deeper understanding of the gene’s contributions to pathophysiological conditions, including immunodeficiencies and autoimmunity.
Scientifically, these knockout models are indispensable in both research and clinical applications. They facilitate high-throughput screening for drug development, the elucidation of genetic disorders, and the exploration of therapeutic targets. By examining the altered characteristics of POU2AF2-deficient cells, scientists can uncover novel mechanisms of disease and potentially identify new biomarkers for therapy.
What sets our POU2AF2 Gene Knockout Cell Lines apart from conventional methods is their precision, reproducibility, and the ability to evaluate gene function in a controlled environment. Unlike other models, these knockout lines provide a clear, direct assessment of the POU2AF2 gene's role, minimizing variability and maximizing experimental reliability.
For researchers and clinicians striving for innovative solutions in immunology and molecular biology, our POU2AF2 Gene Knockout Cell Lines offer a unique resource for advancing knowledge and therapeutic strategies. Our company specializes in cutting-edge genetic tools and has a proven track record in providing high-quality biological products that meet the rigorous demands of modern scientific investigation.
Please note that all services are for research use only. Not intended for any clinical use.
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