Home / POMP Knockout Cell Lines

POMP Knockout Cell Lines

Gene: POMP

Official Full Name: proteasome maturation proteinprovided by HGNC

Gene Summary: The protein encoded by this gene is a molecular chaperone that binds 20S preproteasome components and is essential for 20S proteasome formation. The 20S proteasome is the proteolytically active component of the 26S proteasome complex. The encoded protein is degraded before the maturation of the 20S proteasome is complete. A variant in the 5' UTR of this gene has been associated with KLICK syndrome, a rare skin disorder.[provided by RefSeq, Aug 2010]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22602 POMP Knockout cell line (HeLa) Human POMP 1:3~1:6 Negative Online Inquiry
KO22603 POMP Knockout cell line (HCT 116) Human POMP 1:2~1:4 Negative Online Inquiry
KO22604 POMP Knockout cell line (HEK293) Human POMP 1:3~1:6 Negative Online Inquiry
KO22605 POMP Knockout cell line (A549) Human POMP 1:3~1:4 Negative Online Inquiry

Background

POMP Gene Knockout Cell Lines are genetically modified cellular models designed to facilitate comprehensive studies on the function of the POMP gene, which plays a critical role in various cellular processes including proteasome activity and protein homeostasis. These cell lines have undergone targeted gene disruption techniques, such as CRISPR-Cas9, to ensure the complete ablation of POMP gene expression, thereby allowing researchers to elucidate the gene's specific contributions to cellular physiology, pathophysiology, and potential therapeutic applications.

Key functions of POMP Gene Knockout Cell Lines include the ability to investigate the molecular mechanisms underlying diseases related to proteasomal dysfunction, as well as their role in cellular stress responses. These cell lines serve as powerful tools for researchers to elucidate the cascading effects of POMP depletion, which can influence processes like cell cycle regulation, apoptosis, and immune response activation. In clinical settings, understanding the nuances of how POMP gene function impacts disease mechanisms can lead to novel therapeutic strategies for cancer, neurodegenerative disorders, and other conditions influenced by protein misfolding.

The unique selling points of POMP Gene Knockout Cell Lines include their high specificity, reproducibility, and ease of use. Unlike conventional techniques that may introduce off-target effects or incomplete knockouts, our cell lines are validated for precise gene knockout, ensuring reliable experimental outcomes. Additionally, they come with a well-characterized background to facilitate comparisons and enhance the validity of research findings.

For researchers, clinicians, and development teams focused on innovative therapies, POMP Gene Knockout Cell Lines present valuable opportunities for cutting-edge research and the discovery of new biomarkers and drug targets. They empower scientists with the tools needed to translate genetic insights into actionable biological knowledge, paving the way for advancements in precision medicine.

Our company specializes in creating high-quality, reliable biological products that support and advance scientific research. With extensive expertise in genetic engineering and a commitment to innovation, we provide researchers and clinicians with the crucial tools necessary to make significant contributions in their fields.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.