Gene: POM121C
Official Full Name: POM121 transmembrane nucleoporin Cprovided by HGNC
Gene Summary: Predicted to enable nuclear localization sequence binding activity. Predicted to be a structural constituent of nuclear pore. Predicted to be involved in RNA export from nucleus and protein import into nucleus. Located in nuclear membrane and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO20297 | POM121C Knockout cell line (HeLa) | Human | POM121C | 1:3~1:6 | Negative | Online Inquiry |
KO20298 | POM121C Knockout cell line (HCT 116) | Human | POM121C | 1:2~1:4 | Negative | Online Inquiry |
KO20299 | POM121C Knockout cell line (HEK293) | Human | POM121C | 1:3~1:6 | Negative | Online Inquiry |
KO20300 | POM121C Knockout cell line (A549) | Human | POM121C | 1:3~1:4 | Negative | Online Inquiry |
POM121C Gene Knockout Cell Lines are specially engineered cellular models designed to investigate the biological functions and therapeutic potential of the POM121C gene. The POM121C gene encodes a protein that is pivotal in the nuclear pore complex (NPC) structure and function, playing a crucial role in nucleocytoplasmic transport. These knockout cell lines are generated using advanced CRISPR-Cas9 technology, allowing for precise gene editing that results in targeted gene disruption, which facilitates the study of the gene's role in cellular processes.
Functionally, POM121C Gene Knockout Cell Lines enable researchers to examine the implications of POM121C deficiency on cellular morphology, growth, and response to various stimuli. The absence of this gene can lead to altered nucleocytoplasmic transport, affecting protein localization and gene expression regulation, thus providing insights into its contributions to diseases such as cancer and neurodegeneration. These models are invaluable for studies involving drug discovery, molecular pathogenesis, and the investigation of gene function.
The scientific importance of POM121C Gene Knockout Cell Lines lies in their application across various research fields, particularly in cancer biology, virology, and cell biology. By offering a clear understanding of POM121C’s role, these lines support the development of targeted therapies that could enhance treatment efficacy.
Compared to alternative gene knockout models, POM121C Gene Knockout Cell Lines provide several advantages, including a high efficiency of gene knockout, reproducibility in experimental settings, and compatibility with various downstream applications such as genome-wide CRISPR screens, functional assays, and proteomic analyses. Researchers will appreciate the reliability and specificity these models offer, which enhances confidence in experimental outcomes.
Ultimately, investing in POM121C Gene Knockout Cell Lines means equipping your laboratory with cutting-edge tools for groundbreaking research. Our company specializes in delivering high-quality biological products backed by rigorous science and a commitment to supporting the research community. By choosing our cell lines, researchers can accelerate their discoveries and contribute to advancing scientific knowledge.
Please note that all services are for research use only. Not intended for any clinical use.
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