Gene: PLEKHA6
Official Full Name: pleckstrin homology domain containing A6provided by HGNC
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30216 | PLEKHA6 Knockout cell line (HeLa) | Human | PLEKHA6 | 1:3~1:6 | Negative | Online Inquiry |
KO30217 | PLEKHA6 Knockout cell line (HCT 116) | Human | PLEKHA6 | 1:2~1:4 | Negative | Online Inquiry |
KO30218 | PLEKHA6 Knockout cell line (HEK293) | Human | PLEKHA6 | 1:3~1:6 | Negative | Online Inquiry |
KO30219 | PLEKHA6 Knockout cell line (A549) | Human | PLEKHA6 | 1:3~1:4 | Negative | Online Inquiry |
PLEKHA6 Gene Knockout Cell Lines are genetically engineered cells in which the PLEKHA6 gene has been specifically inactivated or "knocked out." This gene encodes a protein that is believed to play a critical role in various cellular processes, including signal transduction, cytoskeletal organization, and cellular differentiation. The knockout mechanism typically employs CRISPR/Cas9 technology, allowing for precise modifications in the genomic sequence, facilitating studies around gene function and its influence on cellular behavior.
The primary function of these knockout cell lines is to enable researchers to elucidate the physiological roles of the PLEKHA6 gene by examining qualitative and quantitative changes in phenotypes. By observing the differences in cellular responses, survival, proliferation, and differentiation compared to wild-type cells, scientists can gain insights into the potential pathways that PLEKHA6 influences. This can be particularly useful in cancer research, developmental biology, and regenerative medicine.
The scientific importance of PLEKHA6 Gene Knockout Cell Lines lies in their application across various research domains. In clinical settings, these cells can serve as models for disease, providing crucial information about the molecular underpinnings of conditions associated with PLEKHA6 dysregulation. Their use can also extend to drug discovery and the development of targeted therapies, thereby playing a vital role in translational research.
One notable advantage of PLEKHA6 Gene Knockout Cell Lines is their enhanced specificity compared to alternative methods, such as RNA interference or chemical inhibitors, which may produce off-target effects. Additionally, these knockout lines provide stable, reproducible results that are critical for ongoing experimental validations. They empower researchers to generate reliable data that inform further studies, enhancing the overall quality of scientific inquiry.
For researchers and clinicians dedicated to furthering their understanding of gene function and associated pathways, utilizing PLEKHA6 Gene Knockout Cell Lines presents a valuable opportunity. Our company specializes in the production of high-quality, genetically engineered cell lines, ensuring that our products meet rigorous scientific standards and provide reliable results for groundbreaking research. With an extensive portfolio of biological solutions, we are committed to supporting the scientific community in their quest for knowledge and innovation.
Please note that all services are for research use only. Not intended for any clinical use.
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