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PITHD1 Knockout Cell Lines

Gene: PITHD1

Official Full Name: PITH domain containing 1provided by HGNC

Gene Summary: Involved in positive regulation of DNA-templated transcription and positive regulation of megakaryocyte differentiation. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15113 PITHD1 Knockout cell line (HeLa) Human PITHD1 1:3~1:6 Negative Online Inquiry
KO15114 PITHD1 Knockout cell line (HCT 116) Human PITHD1 1:2~1:4 Negative Online Inquiry
KO15115 PITHD1 Knockout cell line (HEK293) Human PITHD1 1:3~1:6 Negative Online Inquiry
KO15116 PITHD1 Knockout cell line (A549) Human PITHD1 1:3~1:4 Negative Online Inquiry

Background

PITHD1 Gene Knockout Cell Lines are a cutting-edge resource in the field of molecular biology, specifically designed to study the effects of inhibiting the PITHD1 gene, which is implicated in various cellular processes and diseases. By employing CRISPR-Cas9 genome editing technology, these cell lines facilitate targeted disruption of the PITHD1 gene, enabling researchers to investigate its role in cellular function, gene expression, and disease mechanisms.

The fundamental mechanism behind the PITHD1 knockout involves the introduction of double-strand breaks in the DNA sequence at the target gene locus, which, upon repair, often leads to insertions or deletions that disrupt normal gene function. This allows for the generation of isogenic cell lines that can serve as robust models for studying gene function in both normal physiology and pathophysiological contexts, including cancer and metabolic disorders.

The scientific importance of PITHD1 Gene Knockout Cell Lines spans numerous research applications, from elucidating the molecular pathways involved in specific diseases to screening for potential therapeutic targets. Researchers and clinicians can leverage these cell lines to design high-throughput assays or validate drug candidates, making them an essential tool in translational medicine.

What sets PITHD1 Gene Knockout Cell Lines apart from alternatives is their high specificity and efficiency in gene editing, which results in reproducible phenotypic outcomes. Unlike traditional methods such as RNA interference, which can lead to off-target effects and variable gene knockdown, our cell lines provide a complete gene knockout, ensuring more reliable and interpretable results.

By investing in PITHD1 Gene Knockout Cell Lines, researchers and clinicians gain access to a precise and effective tool that enhances their ability to unravel complex biological questions and accelerate the development of novel therapies. Our company specializes in providing high-quality, validated biological products, supported by years of expertise in genetic engineering, ensuring that our offerings meet the highest standards of reliability and scientific rigor.

Please note that all services are for research use only. Not intended for any clinical use.

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