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PIH1D2 Knockout Cell Lines

Gene: PIH1D2

Official Full Name: PIH1 domain containing 2provided by HGNC

Gene Summary: Enables small GTPase binding activity. Predicted to be involved in box C/D snoRNP assembly and rRNA processing. Part of protein folding chaperone complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30336 PIH1D2 Knockout cell line (HeLa) Human PIH1D2 1:3~1:6 Negative Online Inquiry
KO30337 PIH1D2 Knockout cell line (HCT 116) Human PIH1D2 1:2~1:4 Negative Online Inquiry
KO30338 PIH1D2 Knockout cell line (HEK293) Human PIH1D2 1:3~1:6 Negative Online Inquiry
KO30339 PIH1D2 Knockout cell line (A549) Human PIH1D2 1:3~1:4 Negative Online Inquiry

Background

PIH1D2 Gene Knockout Cell Lines are specialized genetically modified cell lines designed to facilitate the study of the PIH1D2 gene, which is implicated in pivotal cellular processes such as protein folding and cellular stress responses. These knockout cell lines have been engineered using CRISPR-Cas9 technology to provide an effective means of investigating the functional roles of the PIH1D2 gene by disrupting its expression.

Key to their function, these cell lines allow researchers to observe phenotypic changes and alterations in signaling pathways that arise from the absence of PIH1D2. By providing an unconfounded assessment of PIH1D2's functionality, scientists can elucidate its contributions to disease models, especially in cancer biology and neurodegenerative disorders. The strain’s ability to model specific disease-associated conditions makes it an invaluable tool in both fundamental research and therapeutic development.

The scientific importance of PIH1D2 Gene Knockout Cell Lines is underscored by their broad applications in academic research and clinical settings where understanding gene function is vital. These cell lines can be utilized in drug screening and for probing the underlying molecular pathology of diseases linked to PIH1D2 dysfunction, thus positioning them as critical instruments in translational research.

Compared to traditional methods of gene disruption, such as RNA interference, which often result in partial knockdown with variable efficiency, our PIH1D2 knockout cell lines provide a complete and stable loss of function. This specificity enhances reproducibility and reliability in experiments, offering researchers a more robust platform for their studies.

By leveraging our expertise in genetic engineering and a commitment to high-quality products, we deliver researchers and clinicians the tools necessary to advance understanding in the life sciences. The PIH1D2 Gene Knockout Cell Lines embody our dedication to innovation and excellence, ensuring that our customers gain a competitive edge in their research initiatives.

Please note that all services are for research use only. Not intended for any clinical use.

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