Gene: PHOX2B
Official Full Name: paired like homeobox 2Bprovided by HGNC
Gene Summary: The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome. [provided by RefSeq, Jul 2016]
| Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
|---|---|---|---|---|---|---|
| KOA12503 | PHOX2B Knockout cell line (AC16) | Human | PHOX2B | 1:3-1:4 | negative | Online Inquiry |
| KOA27946 | PHOX2B Knockout cell line (BEAS-2B) | Human | PHOX2B | 1:3~1:4 | negative | Online Inquiry |
| KOA43381 | PHOX2B Knockout cell line (U-2932) | Human | PHOX2B | 1:2-1:4 | negative | Online Inquiry |
| KOA58762 | PHOX2B Knockout cell line (TPC-1) | Human | PHOX2B | 1:5-1:8 | negative | Online Inquiry |
| KOA74185 | PHOX2B Knockout cell line (NCM460) | Human | PHOX2B | 1:2~1:3 | negative | Online Inquiry |
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