Gene: PEAK1
Official Full Name: pseudopodium enriched atypical kinase 1provided by HGNC
Gene Summary: This gene encodes a non-receptor tyrosine kinase that is a member of the new kinase family three (NFK3) family. In migrating cells, the encoded protein is associated with the actin cytoskeleton and focal adhesions and promotes developing focal adhesion elongation. This protein may play a role in the regulation of cell migration, proliferation and cancer metastasis. [provided by RefSeq, Mar 2014]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO15244 | PEAK1 Knockout cell line (HeLa) | Human | PEAK1 | 1:3~1:6 | Negative | Online Inquiry |
KO15245 | PEAK1 Knockout cell line (HCT 116) | Human | PEAK1 | 1:2~1:4 | Negative | Online Inquiry |
KO15246 | PEAK1 Knockout cell line (HEK293) | Human | PEAK1 | 1:3~1:6 | Negative | Online Inquiry |
KO15247 | PEAK1 Knockout cell line (A549) | Human | PEAK1 | 1:3~1:4 | Negative | Online Inquiry |
PEAK1 Gene Knockout Cell Lines are specially engineered cell lines designed to facilitate the study of the PEAK1 (pseudopodium-enriched atypical kinase 1) gene’s role in cellular processes, particularly those linked to cancer progression and metastasis. By employing advanced CRISPR/Cas9 technology, these cell lines exhibit targeted gene disruption, enabling researchers to investigate the precise mechanisms through which PEAK1 influences signaling pathways, cell motility, and tumorigenesis.
The primary function of PEAK1 gene knockout cell lines lies in their ability to provide a versatile platform for functional genomics studies. When the PEAK1 gene is knocked out, researchers can assess variations in cellular behavior such as proliferation, survival, and response to therapeutic agents. This knockout model is essential for dissecting the complex role that PEAK1 plays in cancer biology, offering insights into potential therapeutic targets and biomarkers for patient stratification.
Scientifically, PEAK1 gene knockout cell lines have substantial applications in both research and clinical settings. These cell lines are crucial for drug development, as they enable the identification of novel therapeutic strategies to overcome resistance in cancer treatment. Furthermore, they serve as a valuable tool in biomarker discovery, helping to elucidate prognostic indicators associated with PEAK1 activation in various cancer types.
Compared to alternative knockout strategies or existing cell lines that lack specific PEAK1 gene alterations, our PEAK1 knockout cell lines offer unparalleled precision and reliability. Developed through rigorous validation processes, they ensure reproducible results that are critical for both basic and translational research.
The significance of our PEAK1 Gene Knockout Cell Lines is underscored by their ability to empower researchers and clinicians to uncover intricacies of cancer biology and therapeutic response. By integrating our product into their workflows, users can enhance their experimental outcomes and contribute meaningfully to the field of cancer research.
Our company prides itself on a strong foundation of expertise in genetic engineering and cellular biology, ensuring that our products not only meet the highest standards of quality but also support the scientific community in advancing human health through informed research.
Please note that all services are for research use only. Not intended for any clinical use.
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