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PACC1 Knockout Cell Lines

Gene: PACC1

Official Full Name: proton activated chloride channel 1provided by HGNC

Gene Summary: Enables pH-gated chloride channel activity. Involved in chloride transport. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00916 PACC1 Knockout cell line(HEK293) Human PACC1 1:3~1:6 Negative Online Inquiry
KO01009 PACC1 Knockout cell line (293T) Human PACC1 1:3~1:6 Negative Online Inquiry
KO15391 PACC1 Knockout cell line (HeLa) Human PACC1 1:3~1:6 Negative Online Inquiry
KO15392 PACC1 Knockout cell line (HCT 116) Human PACC1 1:2~1:4 Negative Online Inquiry
KO15393 PACC1 Knockout cell line (A549) Human PACC1 1:3~1:4 Negative Online Inquiry

Background

PACC1 Gene Knockout Cell Lines are specifically engineered cellular models designed to facilitate the study of the PACC1 gene, a significant component implicated in various biological processes such as metabolism, cell signaling, and cancer progression. These knockout cell lines have undergone CRISPR-Cas9 genome editing to ensure the precise disruption of the PACC1 gene sequence, thereby allowing researchers to investigate the gene's function and its effects on cell behavior in a controlled environment.

The key mechanism by which PACC1 Gene Knockout Cell Lines function is through the targeted deletion of the PACC1 gene, resulting in a loss of its associated protein product. This knockout model allows scientists to observe changes in cellular processes, phenotype alterations, and gene expression profiles when PACC1 is absent. Such investigations are crucial for understanding the role this gene plays in stimuli responses, cellular growth, and pathophysiological conditions, thus making them valuable in developmental biology and cancer research.

The scientific importance of these cell lines lies in their applications for elucidating the mechanisms of diseases where PACC1 is suspected to have a regulatory role. They serve as vital tools in drug discovery, functional genomics, and customized therapeutic development. In clinical settings, these knockout models can aid in patient-specific studies and personalized medicine approaches, ensuring that findings are relevant and translatable to patient care.

One of the specific advantages of using PACC1 Gene Knockout Cell Lines is their ability to serve as a reliable platform for comparative studies against wild-type cell lines, establishing a clear baseline to measure functional assays. Additionally, these models can be utilized alongside other cellular systems, enhancing their utility and effectiveness in comprehensive research strategies.

Researchers and clinicians should recognize the value of PACC1 Gene Knockout Cell Lines in addressing biological questions with precision and reliability. Their targeted approach enables a detailed exploration of gene function, significantly contributing to the advancement of scientific knowledge and therapeutic innovations.

At [Company Name], we are dedicated to providing high-quality biological products supported by rigorous scientific validation and expertise. Our commitment to advancing research and healthcare solutions continues to drive us in delivering exceptional products, like the PACC1 Gene Knockout Cell Lines, that meet the evolving needs of researchers and clinicians alike.

Please note that all services are for research use only. Not intended for any clinical use.

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