Gene: OSTF1
Official Full Name: osteoclast stimulating factor 1provided by HGNC
Gene Summary: Osteoclast-stimulating factor-1 is an intracellular protein produced by osteoclasts that indirectly induces osteoclast formation and bone resorption (Reddy et al., 1998 [PubMed 10092216]).[supplied by OMIM, Mar 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO28037 | OSTF1 Knockout cell line (HeLa) | Human | OSTF1 | 1:3~1:6 | Negative | Online Inquiry |
KO28038 | OSTF1 Knockout cell line (HCT 116) | Human | OSTF1 | 1:2~1:4 | Negative | Online Inquiry |
KO28039 | OSTF1 Knockout cell line (HEK293) | Human | OSTF1 | 1:3~1:6 | Negative | Online Inquiry |
KO28040 | OSTF1 Knockout cell line (A549) | Human | OSTF1 | 1:3~1:4 | Negative | Online Inquiry |
OSTF1 Gene Knockout Cell Lines are a specialized biological product designed to facilitate research on the functional genomics and pathophysiological implications of the OSTF1 gene in a range of cellular contexts. These cell lines are generated using CRISPR-Cas9 technology to produce precise deletions of the OSTF1 gene, enabling researchers to investigate its role in cytoskeletal dynamics, cellular signaling pathways, and disease mechanisms—particularly in cellular responses related to cancer biology and immune function.
The primary mechanism by which these cell lines operate involves the disruption of the OSTF1 gene, leading to the loss of its encoded protein, which has been shown to be crucial in actin polymerization and cellular motility. This loss allows researchers to examine the downstream effects on cellular morphology, migratory abilities, and overall biochemical signaling pathways, thus providing invaluable insights into the gene's function and its potential impact in various diseases.
Scientifically, OSTF1 Gene Knockout Cell Lines hold significant importance for both basic and applied biomedical research. In clinical settings, these models are pivotal for drug screening, target validation, and the elucidation of novel therapeutic pathways related to diseases such as cancer and autoimmune disorders.
Compared to other knockout models, our OSTF1 Gene Knockout Cell Lines offer superior reliability and efficiency, ensuring robust performance across various experiments. The precision achieved through our CRISPR-Cas9-derived lines minimizes off-target effects, leading to more reliable data and reproducibility. Additionally, we provide comprehensive technical support and extensive documentation, empowering researchers to harness the full potential of these knockout models.
For researchers and clinicians aiming to illuminate the intricate roles of OSTF1 in health and disease, our OSTF1 Gene Knockout Cell Lines represent a valuable tool in the arsenal of functional genomics. At [Your Company Name], we pride ourselves on our commitment to quality and innovation in biological research products, ensuring that our offerings meet the highest scientific standards and enable groundbreaking discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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