Gene: OR51B4
Official Full Name: olfactory receptor family 51 subfamily B member 4provided by HGNC
Gene Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO15450 | OR51B4 Knockout cell line (HCT 116) | Human | OR51B4 | 1:2~1:4 | Negative | Online Inquiry |
OR51B4 Gene Knockout Cell Lines consist of engineered cells in which the OR51B4 gene has been selectively disrupted through advanced gene editing technologies, such as CRISPR-Cas9. This specialized cell line serves as a vital tool for understanding the biological functions and molecular pathways associated with the OR51B4 gene, which is implicated in olfactory signaling and neurological processes. By removing the expression of OR51B4, researchers can investigate the downstream effects on cell signaling pathways, receptor interactions, and cellular responses to various stimuli.
The primary function of these knockout cell lines is to facilitate comprehensive studies in olfactory sensory neuron function and plasticity. By employing these cells, scientists can identify how the absence of OR51B4 influences cellular behavior in response to odorant molecules and pheromonal signals. This information is crucial for advancing our understanding of sensory biology and could inform therapeutic strategies for neurological disorders, particularly those affecting olfactory functions.
The scientific importance of OR51B4 Gene Knockout Cell Lines extends beyond basic research; their applications in clinical settings can include drug discovery and the development of targeted therapies. These lines enable high-throughput screening of pharmacological agents that may modulate OR51B4-related pathways, offering the potential for novel interventions in conditions such as anosmia or other olfactory dysfunctions.
What sets our OR51B4 Gene Knockout Cell Lines apart from alternatives is their robustness, reproducibility, and the comprehensive validation protocols that ensure the specificity of the gene knockout. Additionally, they come with detailed characterization and extensive support documentation to enhance user experience and application outcomes.
For researchers and clinicians alike, investing in OR51B4 Gene Knockout Cell Lines means gaining access to a powerful platform that advances knowledge in olfactory research while opening new avenues for therapeutic developments. Our company prides itself on expertise in gene editing technologies and the provision of high-quality biological products designed to empower scientific discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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