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NUP62CL Knockout Cell Lines

Gene: NUP62CL

Official Full Name: nucleoporin 62 C-terminal likeprovided by HGNC

Gene Summary: This gene encodes a protein containing a domain found in nucleoporins which are glycoproteins found in nuclear pore complexes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15567 NUP62CL Knockout cell line (HeLa) Human NUP62CL 1:3~1:6 Negative Online Inquiry
KO15568 NUP62CL Knockout cell line (HCT 116) Human NUP62CL 1:2~1:4 Negative Online Inquiry
KO15569 NUP62CL Knockout cell line (HEK293) Human NUP62CL 1:3~1:6 Negative Online Inquiry
KO15570 NUP62CL Knockout cell line (A549) Human NUP62CL 1:3~1:4 Negative Online Inquiry

Background

NUP62CL Gene Knockout Cell Lines are advanced biological models designed for the study of nucleocytoplasmic transport and cellular signaling pathways. These cell lines specifically feature targeted deletions of the NUP62CL gene, which encodes a protein integral to the nuclear pore complex. By eliminating the functional protein, researchers can explore the role of NUP62CL in transport mechanisms and its implications in various cellular processes, including DNA repair, gene expression regulation, and cell cycle control.

Key functions of the NUP62CL Gene Knockout Cell Lines are rooted in their ability to enable the detailed investigation of molecular interactions and pathways affected by disrupted nucleocytoplasmic transport. The knockout models allow scientists to monitor alterations in cellular behavior, enabling insight into essential processes such as mRNA export and protein synthesis, which are pivotal in understanding diseases like cancer and neurodegenerative disorders.

The scientific importance of these cell lines extends to both research and clinical applications, where they serve as valuable tools for drug screening and therapeutic targeting. Failure of nucleocytoplasmic transport mechanisms has been implicated in various pathologies, making these models essential for examining potential treatment strategies and biomarker identification.

Compared to traditional models, NUP62CL Gene Knockout Cell Lines offer precise genetic modifications that yield reproducible and consistent results, minimizing the variability seen in other systems. The knockout approach enables focused analysis of the gene's functions without confounding effects from wild-type variants, thus providing clear insights into its role in cell biology.

For researchers and clinicians alike, these cellular tools represent a significant advancement in the quest to unlock complex biological questions and drive forward therapeutic innovations. The potential to illuminate new pathways and offer insights into disease mechanisms makes this product invaluable in contemporary biomedical research.

Our company brings extensive expertise in generating high-quality cell lines and providing innovative solutions to enhance research productivity, ensuring that our customers have access to cutting-edge tools that facilitate advancements in biological science.

Please note that all services are for research use only. Not intended for any clinical use.

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