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NUMBL Knockout Cell Lines

Gene: NUMBL

Official Full Name: NUMB like endocytic adaptor proteinprovided by HGNC

Gene Summary: Involved in cytokine-mediated signaling pathway. Predicted to be active in cytoplasm and glutamatergic synapse. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO11346 NUMBL Knockout cell line (HeLa) Human NUMBL 1:3~1:6 Negative Online Inquiry
KO11347 NUMBL Knockout cell line (HCT 116) Human NUMBL 1:2~1:4 Negative Online Inquiry
KO11348 NUMBL Knockout cell line (HEK293) Human NUMBL 1:3~1:6 Negative Online Inquiry
KO11349 NUMBL Knockout cell line (A549) Human NUMBL 1:3~1:4 Negative Online Inquiry

Background

NUMBL Gene Knockout Cell Lines are a cutting-edge genetic tool designed for the targeted disruption of the NUMBL gene, a critical player in various signaling pathways and developmental processes. These cell lines are engineered using CRISPR-Cas9 technology, which allows for precise gene editing and knockout with high efficiency and specificity. By effectively silencing the NUMBL gene, researchers can investigate its functions and interactions in cellular contexts, facilitating a deeper understanding of its role in cell differentiation, cancer biology, and neurodevelopmental disorders.

The primary function of NUMBL Gene Knockout Cell Lines lies in their ability to elucidate the physiological and pathological implications of NUMBL gene absence. In research settings, scientists can study the resultant phenotypic and molecular changes that occur in these knockout models, thereby providing insights into the signaling pathways in which NUMBL is involved. This can lead to significant advancements in therapeutic strategies targeting related diseases, as well as the potential development of new biomarker candidates.

What sets NUMBL Gene Knockout Cell Lines apart from alternative gene-editing tools is their high fidelity and minimal off-target effects achieved through advanced CRISPR methodology. Additionally, these cell lines are fully validated, ensuring that researchers can trust the results obtained for reproducibility and clarity in their studies. The specificity and dependability of these knockout lines make them exceptionally valuable for both academia and industry applications, including drug discovery and genetic research.

For researchers and clinicians committed to understanding complex biological processes or developing targeted therapies, NUMBL Gene Knockout Cell Lines offer an indispensable resource. Their utility in various experimental designs enables translational applications that bridge fundamental research with clinical innovation, facilitating the advancement of personalized medicine.

As a leader in innovative biological products, our company is dedicated to providing researchers with high-quality, versatile tools that enhance scientific inquiry and drive breakthroughs in life sciences. We pride ourselves on rigorous quality control and continuous support, ensuring that our products, including the NUMBL Gene Knockout Cell Lines, meet the highest standards in research excellence.

Please note that all services are for research use only. Not intended for any clinical use.

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