Gene: NUDT19
Official Full Name: nudix hydrolase 19provided by HGNC
Gene Summary: Predicted to enable magnesium ion binding activity. Predicted to be involved in acyl-CoA metabolic process and coenzyme A catabolic process. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO15579 | NUDT19 Knockout cell line (HeLa) | Human | NUDT19 | 1:3~1:6 | Negative | Online Inquiry |
KO15580 | NUDT19 Knockout cell line (HCT 116) | Human | NUDT19 | 1:2~1:4 | Negative | Online Inquiry |
KO15581 | NUDT19 Knockout cell line (HEK293) | Human | NUDT19 | 1:3~1:6 | Negative | Online Inquiry |
KO15582 | NUDT19 Knockout cell line (A549) | Human | NUDT19 | 1:3~1:4 | Negative | Online Inquiry |
NUDT19 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to facilitate the study of the NUDT19 gene's biological functions. These cell lines have been developed using advanced CRISPR-Cas9 gene-editing technology, allowing for the precise knockout of the NUDT19 gene, which encodes a Nudix hydrolase enzyme implicated in nucleotide metabolism and cellular signaling pathways. By removing the functionality of this gene, researchers can explore the downstream effects on cell behavior, proliferation, and the response to various stressors, thereby elucidating the role of NUDT19 in health and disease.
The knockout mechanism allows scientists to perform functional assays that reveal the pathways affected by NUDT19 disruption. This can lead to insights into its contribution to oxidative stress responses, DNA repair processes, and its potential role in cancer biology, as aberrations in nucleotide metabolism have been linked to tumorigenesis. Thus, NUDT19 Gene Knockout Cell Lines serve as an invaluable tool for both basic research and translational applications, including drug development and therapeutic interventions.
Compared to traditional methods of gene expression analysis or overexpression studies, these knockout cell lines offer a more accurate and controlled environment to study the absence of NUDT19, allowing for the clear delineation of gene function. The specificity and precision of the CRISPR technology used ensures minimal off-target effects, heightening the validity of experimental results.
These cell lines are particularly advantageous for researchers and clinicians focused on metabolic disorders, cancer research, and genetic assays, providing a reliable model for experimental reproducibility.
With years of expertise in genetic engineering and cell line development, our company is dedicated to providing high-quality, scientifically robust tools that empower researchers in their quest to understand complex biological systems. Our NUDT19 Gene Knockout Cell Lines exemplify this commitment, offering unmatched reliability and performance for your research needs.
Please note that all services are for research use only. Not intended for any clinical use.
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