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NPEPPS Knockout Cell Lines

Gene: NPEPPS

Official Full Name: aminopeptidase puromycin sensitiveprovided by HGNC

Gene Summary: This gene encodes the puromycin-sensitive aminopeptidase, a zinc metallopeptidase which hydrolyzes amino acids from the N-terminus of its substrate. The protein has been localized to both the cytoplasm and to cellular membranes. This enzyme degrades enkaphalins in the brain, and studies in mouse suggest that it is involved in proteolytic events regulating the cell cycle. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO02313 NPEPPS Knockout cell line (HeLa) Human NPEPPS 1:3~1:6 Negative Online Inquiry
KO02314 NPEPPS Knockout cell line (HCT 116) Human NPEPPS 1:2~1:4 Negative Online Inquiry
KO02315 NPEPPS Knockout cell line (HEK293) Human NPEPPS 1:3~1:6 Negative Online Inquiry

Background

NPEPPS Gene Knockout Cell Lines are precisely engineered cellular models designed to facilitate the study of the NPEPPS gene, which encodes an enzyme involved in various biological processes, including peptide metabolism and signal transduction. These knockout cell lines effectively disable the NPEPPS gene, allowing researchers to investigate the resulting phenotypic changes and elucidate the gene's role in cellular functions, disease mechanisms, and therapeutic contexts.

The primary mechanism of action for these cell lines involves the targeted deletion of the NPEPPS gene through advanced gene-editing technologies, such as CRISPR-Cas9. This allows for the accurate assessment of the gene's contribution to physiological and pathological states, including cancer progression, metabolic disorders, and neurodegenerative diseases. By providing a controlled environment in which the gene's absence can be studied, these knockout cell lines serve as a powerful tool for both basic and applied research.

The scientific importance of NPEPPS Gene Knockout Cell Lines lies in their applications across multiple fields, including pharmacology, genetics, and disease modeling. They enable researchers to uncover critical insights into drug response mechanisms, identify novel therapeutic targets, and enhance the understanding of gene functions in health and disease. In clinical research settings, these knockout models can aid in the development of personalized medicine approaches, improving patient outcomes through tailored therapies.

What sets the NPEPPS Gene Knockout Cell Lines apart from traditional models is their high specificity and reliability. Unlike standard cell lines that may carry uncharacterized genetic modifications, these knockout lines provide a clean, defined background for studying the effects of NPEPPS gene deletion. Additionally, our commitment to rigorous validation and quality control ensures that researchers can trust their results, reducing experimental variability.

Investing in NPEPPS Gene Knockout Cell Lines is an invaluable asset for researchers, clinicians, and biotechnologists alike. By utilizing these advanced models, users can accelerate their understanding of complex biological systems and contribute to cutting-edge discoveries in gene function and therapeutic development. Our company prides itself on delivering innovative biological products backed by extensive scientific expertise, ensuring that customers receive exceptional quality and support for their research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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