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NME6 Knockout Cell Lines

Gene: NME6

Official Full Name: NME/NM23 nucleoside diphosphate kinase 6provided by HGNC

Gene Summary: Nucleoside diphosphate (NDP) kinases (EC 2.7.4.6), such as NME6, are ubiquitous enzymes that catalyze transfer of gamma-phosphates, via a phosphohistidine intermediate, between nucleoside and dioxynucleoside tri- and diphosphates (Mehus et al., 1999 [PubMed 10453732]).[supplied by OMIM, Jul 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32162 NME6 Knockout cell line (HeLa) Human NME6 1:3~1:6 Negative Online Inquiry
KO32163 NME6 Knockout cell line (HCT 116) Human NME6 1:2~1:4 Negative Online Inquiry
KO32164 NME6 Knockout cell line (HEK293) Human NME6 1:3~1:6 Negative Online Inquiry
KO32165 NME6 Knockout cell line (A549) Human NME6 1:3~1:4 Negative Online Inquiry

Background

NME6 Gene Knockout Cell Lines are genetically modified cellular models designed to facilitate in-depth investigations of the NME6 gene, a member of the NME family known for its involvement in cellular processes such as DNA synthesis and repair. These cell lines have been created through precise gene editing techniques, resulting in the disruption of the NME6 gene sequence. This knockout model allows researchers to study the resultant phenotypic effects, providing valuable insights into the biological functions that NME6 influences.

These cell lines function by serving as a comparative platform against wild-type cells, thus enabling scientists to evaluate alterations in cellular behavior, signaling pathways, and gene expression profiles attributed to the knockout of NME6. The mechanisms underlying these changes can lead to revelations about cellular responses to stress, proliferation, and differentiation, offering clues for understanding disease states or potential therapeutic targets.

The scientific importance of NME6 Gene Knockout Cell Lines extends beyond fundamental research; they are instrumental in preclinical studies aimed at cancer biology, genetic disorders, and drug development. They allow for the exploration of NME6's role in tumorigenesis, making them highly applicable in the study of cancer metabolism and therapy resistance.

One of the significant advantages of our NME6 Gene Knockout Cell Lines lies in their customization and validation, ensuring high-titer generation approved by rigorous testing protocols. Unlike alternative models that may rely on nonspecific knockdowns or overexpression systems, these knockout lines provide a clear, target-specific approach that minimizes off-target effects, leading to more reliable data.

For researchers and clinicians, the immediate value of these cell lines resides in their robustness and reproducibility, crucial factors when designing experiments. The ability to produce reliable results accelerates the drug discovery process and enhances translational research aimed at innovative therapeutic strategies.

Our company, with years of expertise in cell line development and gene editing technologies, is dedicated to providing precision tools for life sciences research. We are committed to supporting the scientific community by delivering high-quality biological products that empower groundbreaking discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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