Home / NEGR1 Knockout Cell Lines

NEGR1 Knockout Cell Lines

Gene: NEGR1

Official Full Name: neuronal growth regulator 1provided by HGNC

Gene Summary: Predicted to be involved in cell adhesion and regulation of synapse assembly. Predicted to act upstream of or within several processes, including cholesterol homeostasis; lipid droplet formation; and nervous system development. Predicted to be located in extracellular region and plasma membrane. Predicted to be active in postsynaptic density. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21004 NEGR1 Knockout cell line (HeLa) Human NEGR1 1:3~1:6 Negative Online Inquiry

Background

NEGR1 Gene Knockout Cell Lines are specially engineered cellular models that have had the NEGR1 gene, prominently associated with neurodevelopmental processes and psychiatric disorders, specifically disrupted or inactivated. These cell lines serve as invaluable tools for scientists to study the physiological and pathological roles of the NEGR1 gene, providing insights into mechanisms underlying various neuropsychiatric conditions such as schizophrenia and mood disorders.

The primary function of the NEGR1 Gene Knockout Cell Lines lies in their ability to mimic the altered genetic background often observed in human diseases. By completely knocking out the NEGR1 gene, these cell lines allow researchers to investigate the cellular consequences of its absence, elucidate signaling pathways, and assess the impact on neuronal differentiation, synaptic function, and cognitive behaviors. Mechanistically, alterations induced by the knockout can be analyzed using various biochemical assays, proteomics, and genomic techniques, facilitating a comprehensive understanding of the gene's role in neurobiology.

Scientific applications of NEGR1 Knockout Cell Lines are broad, extending from fundamental research in neurobiology to translational studies aimed at developing therapeutic strategies for psychiatric disorders. Their utility in drug discovery and personalized medicine, particularly in identifying potential pharmaceutical compounds that could target the pathways influenced by NEGR1, is of paramount importance.

The advantages of NEGR1 Gene Knockout Cell Lines over traditional animal models or wild-type cell lines include a highly controlled environment for experimentation, reduced biological variability, and the potential for high-throughput screening applications. Additionally, their availability accelerates the research process by providing readily accessible models for lab studies without the ethical complexities associated with animal research.

For researchers and clinicians focused on neurodevelopmental studies, our NEGR1 Gene Knockout Cell Lines represent a cutting-edge resource that bridges the gap between basic science and clinical application. By investing in our products, users gain access to reliably characterized cell lines developed with rigorous quality control measures. Our company is dedicated to furthering scientific knowledge and offers a diverse portfolio of biological products, underscored by our commitment to excellence and innovation in research tools.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.