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NECAB2 Knockout Cell Lines

Gene: NECAB2

Official Full Name: N-terminal EF-hand calcium binding protein 2provided by HGNC

Gene Summary: The protein encoded by this gene is a neuronal calcium-binding protein that binds to and modulates the function of at least two receptors, adenosine A(2A) receptor and metabotropic glutamate receptor type 5. [provided by RefSeq, Jul 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21622 NECAB2 Knockout cell line (HEK293) Human NECAB2 1:3~1:6 Negative Online Inquiry
KO21623 NECAB2 Knockout cell line (A549) Human NECAB2 1:3~1:4 Negative Online Inquiry

Background

NECAB2 Gene Knockout Cell Lines are engineered cellular models designed to facilitate the study of the NECAB2 gene, a critical component involved in cellular signaling and neuronal function. By employing cutting-edge CRISPR-Cas9 gene editing technology, these cell lines exhibit a complete knockout of the NECAB2 gene, allowing researchers to investigate its influence on various biological processes without the confounding effects of its expression.

The primary mechanism behind these knockout cell lines is the targeted disruption of the NECAB2 gene, leading to the absence of its protein product. This allows scientists to assess the gene’s role in physiological and pathological contexts, particularly in neurodegenerative diseases, synaptic function, and possibly cancer biology. By analyzing the resultant phenotypic and genotypic changes, researchers can gain insights into NECAB2's contributions to signaling pathways and disease mechanisms.

Scientifically, NECAB2 Gene Knockout Cell Lines hold significant importance in both basic and applied research. These models offer valuable platforms for drug discovery, toxicology studies, and the elucidation of gene function, making them essential tools in translational medicine. The ability to manipulate gene expression in diverse treatments enhances our understanding of gene-disease associations and opens new avenues for targeted therapeutics.

One of the standout advantages of NECAB2 Gene Knockout Cell Lines is their specificity and reliability compared to traditional knockout models, which may exhibit off-target effects or incomplete gene inactivation. This precision ensures that researchers can confidently attribute observed changes specifically to the absence of NECAB2, thereby improving the validity of experimental outcomes.

For researchers and clinicians, the value of NECAB2 Gene Knockout Cell Lines lies in their potential to drive innovation in the understanding and treatment of diseases linked to NECAB2 dysfunction. The robustness of these cell lines, accompanied by our company’s dedication to high-quality biological products and support, positions them as a key resource in advancing scientific discovery and therapeutic development. Our expertise and commitment to excellence ensure that you receive not just a product, but a solution tailored to your research needs.

Please note that all services are for research use only. Not intended for any clinical use.

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