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NCAM2 Knockout Cell Lines

Gene: NCAM2

Official Full Name: neural cell adhesion molecule 2provided by HGNC

Gene Summary: The protein encoded by this gene belongs to the immunoglobulin superfamily. It is a type I membrane protein and may function in selective fasciculation and zone-to-zone projection of the primary olfactory axons. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO04505 NCAM2 Knockout cell line (HeLa) Human NCAM2 1:3~1:6 Negative Online Inquiry

Background

NCAM2 Gene Knockout Cell Lines are genetically engineered cellular models lacking the neural cell adhesion molecule 2 (NCAM2) gene, a key player in neural development, cell adhesion, and synapse formation. These cell lines enable researchers to investigate the functional role of NCAM2 in various biological processes, particularly in neurobiology and developmental biology. By disrupting NCAM2 expression, these knockout cell lines provide critical insights into the molecular mechanisms underlying neural connectivity and plasticity, as well as the contributions of NCAM2 to diseases such as schizophrenia and autism spectrum disorders.

The key function of these NCAM2 knockout cell lines revolves around their ability to serve as a tool for studying the impact of NCAM2 disruption on cellular behavior, signaling pathways, and interactions with other neuronal components. This model facilitates the investigation of downstream signaling events that may alter neuronal function and development, ultimately offering potential therapeutic targets for NCAM2-related pathologies.

The scientific importance of NCAM2 Gene Knockout Cell Lines lies in their diverse applications within research settings including genetic studies, drug discovery, and regenerative medicine. They allow for the exploration of aberrant neuronal development mechanisms and promote an understanding of how adhesion molecules influence synaptic formation and neural network stability.

One of the unique advantages of our NCAM2 Gene Knockout Cell Lines is their high specificity and reproducibility, enabling consistent results across various experiments. Unlike conventional models, these cell lines eliminate the confounding effects of the NCAM2 gene, leading to clearer interpretations of experimental data. Additionally, our cell lines are readily amenable to CRISPR/Cas9 or other gene-editing techniques, ensuring compatibility with advanced research methodologies.

For researchers, clinicians, and pharmaceutical companies invested in neurobiological research or developing interventions for neural disorders, NCAM2 Gene Knockout Cell Lines represent an invaluable resource. Their application can accelerate the identification of novel pharmaceutical targets and enhance understanding of complex neurodevelopmental diseases.

As a company committed to advancing scientific research, we offer a comprehensive suite of genetic models, coupled with expert support and resources tailored to empower researchers in their quest for new insights and breakthroughs.

Please note that all services are for research use only. Not intended for any clinical use.

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