Gene: MTERF4
Official Full Name: mitochondrial transcription termination factor 4provided by HGNC
Gene Summary: Enables rRNA binding activity. Predicted to be involved in mitochondrial ribosome assembly and mitochondrial transcription. Predicted to act upstream of or within several processes, including camera-type eye development; protein targeting to mitochondrion; and ribosome assembly. Located in cytosol and mitochondrion. Part of mitochondrial large ribosomal subunit. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26585 | MTERF4 Knockout cell line (HeLa) | Human | MTERF4 | 1:3~1:6 | Negative | Online Inquiry |
KO26586 | MTERF4 Knockout cell line (HCT 116) | Human | MTERF4 | 1:2~1:4 | Negative | Online Inquiry |
KO26587 | MTERF4 Knockout cell line (HEK293) | Human | MTERF4 | 1:3~1:6 | Negative | Online Inquiry |
KO26588 | MTERF4 Knockout cell line (A549) | Human | MTERF4 | 1:3~1:4 | Negative | Online Inquiry |
MTERF4 Gene Knockout Cell Lines are engineered cellular models specifically designed to facilitate the study of the MTERF4 gene and its functional implications. MTERF4, a member of the mitochondrial transcription termination factor family, plays a crucial role in regulating mitochondrial gene expression and cellular metabolism. By effectively silencing the MTERF4 gene, these knockout cell lines allow researchers to investigate the gene's contributions to mitochondrial function, energy production, and cellular physiology.
The primary function of MTERF4 is to terminate mitochondrial transcription, thereby influencing the synthesis of critical mitochondrial proteins that are integral to ATP generation and cellular respiration. The knockout of this gene leads to alterations in mitochondrial dynamics, promoting insights into metabolic anomalies and various diseases linked to mitochondrial dysfunction, such as neurodegenerative disorders and myopathies. By providing a platform for in-depth study, these cell lines contribute significantly to the understanding of mitochondrial biology and its impact on human health.
Scientifically, these cell lines are paramount in both research and clinical applications, enabling the exploration of therapeutic strategies targeting mitochondrial dysfunction. They serve as vital tools in drug discovery, where the efficacy of potential treatments for mitochondrial diseases can be assessed accurately. Furthermore, researchers can use these knockout models to elucidate gene interactions and regulatory networks involving MTERF4, thereby advancing the field of genomics and molecular biology.
Compared to traditional cell lines that might express MTERF4, the knockout variants provide a more controlled environment for experiments, minimizing confounding variables and enhancing the reliability of results. This specificity makes the MTERF4 Gene Knockout Cell Lines an indispensable resource for researchers looking to deepen their understanding of mitochondrial physiology and its associated pathologies.
Investing in MTERF4 Gene Knockout Cell Lines equips researchers and clinicians with a profound tool to unravel the complexities of mitochondrial function, thereby accelerating advances in therapeutic development and clinical innovation. Our company, recognized for its expertise in providing high-quality biological products, is committed to supporting research endeavors with cutting-edge cellular models that drive scientific excellence and discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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