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MSL3 Knockout Cell Lines

Gene: MSL3

Official Full Name: MSL complex subunit 3provided by HGNC

Gene Summary: This gene encodes a nuclear protein that is similar to the product of the Drosophila male-specific lethal-3 gene. The Drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus, the human protein is thought to play a similar function in chromatin remodeling and transcriptional regulation, and it has been found as part of a complex that is responsible for histone H4 lysine-16 acetylation. This gene can undergo X inactivation. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2, 7 and 8. [provided by RefSeq, Jul 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO31390 MSL3 Knockout cell line (HeLa) Human MSL3 1:3~1:6 Negative Online Inquiry
KO31391 MSL3 Knockout cell line (HCT 116) Human MSL3 1:2~1:4 Negative Online Inquiry
KO31392 MSL3 Knockout cell line (HEK293) Human MSL3 1:3~1:6 Negative Online Inquiry
KO31393 MSL3 Knockout cell line (A549) Human MSL3 1:3~1:4 Negative Online Inquiry

Background

MSL3 Gene Knockout Cell Lines are a revolutionary tool in genetic research, designed to facilitate the study of the MSL3 gene's role in various biological processes. By utilizing CRISPR-Cas9 technology, these cell lines possess targeted deletions of the MSL3 gene, enabling researchers to analyze the consequences of this gene's absence on cellular functions and pathways. The knockout of the MSL3 gene, known for its involvement in dosage compensation and chromatin remodeling, provides a unique model to investigate its implications in gene expression regulation and developmental biology.

The primary function of MSL3 Gene Knockout Cell Lines lies in their capacity to elucidate the multifaceted roles of the MSL3 protein. Researchers can utilize these cell lines to explore alterations in gene transcription, chromatin structure, and the overall epigenetic landscape. This enables identification of pathways that may be modulated in various conditions, such as cancer or genetic disorders. The insights gained from studies using these knockout cell lines are vital for advancing our understanding of genetic regulation and its implications in health and disease.

In the realm of scientific research and clinical applications, MSL3 Gene Knockout Cell Lines stand out due to their precise genetic modifications, which offer a definitive approach for investigations into gene function. Compared to traditional methods, these engineered cell lines reduce the ambiguity often associated with less specific gene manipulation techniques, yielding clearer results with repeatable outcomes. Their targeted nature minimizes off-target effects and allows for more reliable data collection.

Moreover, the advanced cryopreservation techniques used in the production of these cell lines ensure an extended shelf life and consistent performance across multiple experiments, which is crucial for the accelerated pace of modern research. The gene knockout cell lines are not only compelling for basic research but also hold potential for therapeutic advancements, particularly in the development of specific targeted therapies for diseases linked to dysregulation of the MSL3 gene.

Our company is committed to supporting the scientific community with high-quality, precisely engineered biological products, backed by extensive expertise in molecular biology. The MSL3 Gene Knockout Cell Lines exemplify our dedication to providing innovative solutions that empower researchers and clinicians alike to push the boundaries of scientific discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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