Gene: MPP2
Official Full Name: MAGUK p55 scaffold protein 2provided by HGNC
Gene Summary: Palmitoylated membrane protein 2 is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. Palmitoylated membrane protein 2 contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO04905 | MPP2 Knockout cell line (HeLa) | Human | MPP2 | 1:3~1:6 | Negative | Online Inquiry |
KO04906 | MPP2 Knockout cell line (HCT 116) | Human | MPP2 | 1:2~1:4 | Negative | Online Inquiry |
KO04907 | MPP2 Knockout cell line (HEK293) | Human | MPP2 | 1:3~1:6 | Negative | Online Inquiry |
KO04908 | MPP2 Knockout cell line (A549) | Human | MPP2 | 1:3~1:4 | Negative | Online Inquiry |
MPP2 Gene Knockout Cell Lines are genetically engineered cell lines designed specifically for the targeted knockout of the MPP2 gene, a significant component involved in various cellular functions, including motility, adhesion, and signaling pathways. These knockout models allow researchers to elucidate the biological roles and mechanisms governed by MPP2, providing invaluable insights into its contributions to processes such as cellular differentiation and immune response modulation.
The primary function of these cell lines is to facilitate the study of MPP2's role in cellular dynamics and pathology. The knockout technique employed typically involves CRISPR/Cas9 technology, which introduces specific mutations in the MPP2 gene. This results in the loss of function of the corresponding protein, enabling researchers to observe the resulting phenotypic and functional changes. By providing a controlled environment to assess how the absence of MPP2 alters various biological processes, these cell lines serve as powerful tools for dissecting the gene’s involvement in diseases, including cancer and autoimmune disorders.
In research and clinical settings, MPP2 Gene Knockout Cell Lines offer significant scientific value, primarily in drug development and biomarker identification. They empower researchers to identify potential therapeutic targets and evaluate drug efficacy in a model that closely mimics the pathological state of diseases associated with MPP2 dysregulation.
One of the key advantages of using MPP2 Gene Knockout Cell Lines over traditional models is their specificity and reproducibility. Unlike transgenic models that may exhibit variable expression levels or off-target effects, these knockout lines provide a consistent platform for experimental integrity. Additionally, they can be easily integrated into high-throughput screening assays, streamlining the investigation process.
Ultimately, MPP2 Gene Knockout Cell Lines are an essential addition to the toolkit of researchers and clinicians involved in genetic studies and therapeutic developments. By choosing this product, users can enhance the preciseness of their experiments and accelerate scientific discovery. Our company prides itself on delivering high-quality, innovative biological products that are backed by extensive expertise in genetic engineering and cellular biology, ensuring that our clients have access to the best resources for their research endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.