Gene: MITD1
Official Full Name: microtubule interacting and trafficking domain containing 1provided by HGNC
Gene Summary: Abscission, the separation of daughter cells at the end of cytokinesis, is effected by endosomal sorting complexes required for transport III (ESCRT-III). The protein encoded by this gene functions as a homodimer, with the N-termini binding to a subset of ESCRT-III subunits and the C-termini binding to membranes. The encoded protein regulates ESCRT-III activity and is required for proper cytokinesis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26670 | MITD1 Knockout cell line (HeLa) | Human | MITD1 | 1:3~1:6 | Negative | Online Inquiry |
KO26671 | MITD1 Knockout cell line (HCT 116) | Human | MITD1 | 1:2~1:4 | Negative | Online Inquiry |
KO26672 | MITD1 Knockout cell line (HEK293) | Human | MITD1 | 1:3~1:6 | Negative | Online Inquiry |
KO26673 | MITD1 Knockout cell line (A549) | Human | MITD1 | 1:3~1:4 | Negative | Online Inquiry |
MITD1 Gene Knockout Cell Lines are a valuable tool designed for researchers interested in the functional analysis of the MITD1 gene, which encodes for a protein implicated in various cellular processes, including cell proliferation, differentiation, and response to stress. By utilizing CRISPR-Cas9 technology, these cell lines feature targeted deletions of the MITD1 gene, enabling precise studies of gene function and the elucidation of downstream effects in cellular pathways.
The primary function of the MITD1 Gene Knockout Cell Lines is to facilitate the investigation of the biological role of the MITD1 protein. The absence of this gene allows researchers to observe alterations in cellular behavior, providing insight into the protein's involvement in critical processes such as apoptosis, cell cycle regulation, and metabolic functions. Furthermore, the knockout model aids in identifying compensatory pathways activated in response to the loss of MITD1, thereby contributing to a broader understanding of homeostatic mechanisms.
In both research and clinical settings, these cell lines hold significant scientific importance. They serve as platforms for drug discovery, allowing scientists to evaluate the efficacy of novel therapeutic compounds that might target cell lines lacking the MITD1 gene. Additionally, they can be instrumental in studying diseases where MITD1 expression is dysregulated, including various cancers and metabolic disorders.
What sets MITD1 Gene Knockout Cell Lines apart from alternatives is the precision of the knockout achieved through state-of-the-art gene editing techniques, ensuring high specificity and reproducibility in experimental outcomes. Unlike traditional knockout methods that may produce off-target effects, our cell lines significantly reduce the potential for confounding variables, making results more reliable and interpretable.
For researchers and clinicians, the value of MITD1 Gene Knockout Cell Lines lies in their ability to provide robust, high-quality models for in-depth genetic studies. The ability to conduct precise experiments on gene function while minimizing extraneous variability enables advancements in the understanding of disease mechanisms and the development of targeted treatments.
Our company is committed to fostering scientific innovation, leveraging our expertise in genetic manipulation and cell line development to provide cutting-edge research tools like the MITD1 Gene Knockout Cell Lines. With a focus on quality and researchers' needs, we empower scientific communities to unravel the complexities of biology and improve patient outcomes.
Please note that all services are for research use only. Not intended for any clinical use.
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