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MIEN1 Knockout Cell Lines

Gene: MIEN1

Official Full Name: migration and invasion enhancer 1provided by HGNC

Gene Summary: Involved in negative regulation of apoptotic process; positive regulation of cell migration; and positive regulation of filopodium assembly. Located in cytoplasmic side of plasma membrane and cytosol. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24955 MIEN1 Knockout cell line (HeLa) Human MIEN1 1:3~1:6 Negative Online Inquiry
KO24956 MIEN1 Knockout cell line (HCT 116) Human MIEN1 1:2~1:4 Negative Online Inquiry
KO24957 MIEN1 Knockout cell line (HEK293) Human MIEN1 1:3~1:6 Negative Online Inquiry
KO24958 MIEN1 Knockout cell line (A549) Human MIEN1 1:3~1:4 Negative Online Inquiry

Background

MIEN1 Gene Knockout Cell Lines are specialized cellular models specifically engineered to disable the MIEN1 gene, which is known to play a critical role in various cellular processes, including motility and tumor progression. These cell lines are created through advanced CRISPR/Cas9 genome editing techniques, allowing for precise and reliable disruption of the MIEN1 gene. By eliminating the influence of this gene, researchers can gain invaluable insights into its function and the molecular pathways it affects, thus facilitating a deeper understanding of its involvement in oncogenesis and metastasis.

The main mechanism of MIEN1 Gene Knockout Cell Lines lies in their ability to serve as a powerful tool for studying gene function and the resultant phenotypic changes in vitro. Upon gene knockout, these cell lines exhibit significant alterations in characteristics such as cell adhesion, migration, and invasion, making them ideal models for elucidating the biological roles of MIEN1 in cancer. In addition, the availability of these knockout models provides researchers with the capability to perform drug screening, therapeutic target validation, and mechanistic studies, further enhancing the potential for clinical translation.

From a scientific perspective, MIEN1 Gene Knockout Cell Lines are invaluable for broadening our understanding of cancer biology and developing novel therapeutic strategies. Their use in research settings can lead to breakthroughs in identifying new biomarkers for early diagnosis, monitoring disease progression, and discovering targets for intervention in malignant diseases characterized by aberrant MIEN1 expression.

What sets MIEN1 Gene Knockout Cell Lines apart from traditional cell lines is their specificity and reliability in mimicking the loss-of-function scenarios found in actual tumors. Unlike generic cell lines, our knockout models are crafted for robust performance in functional assays, allowing researchers to achieve more reproducible and interpretable results. By choosing our MIEN1 Gene Knockout Cell Lines, scientists and clinicians can enhance their research efforts with high-quality, well-characterized products designed to meet evolving experimental needs.

Our company prides itself on its expertise in genetic engineering and molecular biology, with a commitment to providing cutting-edge solutions for research and clinical use. By leveraging our extensive background, we aim to support advancements in the field of cancer research and beyond, thereby contributing to the development of innovative treatments with the potential to improve patient outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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