Gene: MIA2
Official Full Name: MIA SH3 domain ER export factor 2provided by HGNC
Gene Summary: This gene encodes s receptor in the endoplasmic reticulum, which plays a role in the export of large pre-chylomicrons and pre-very low density lipoproteins (pre-VLDLs). Three major classes of transcripts are generated from this gene- melanoma inhibitory activity 2-specific transcripts, cTAGE family member 5-specific transcripts and transcripts that include exons from both these transcript species (TANGO1-like or TALI). Additionally, alternative splicing in these transcripts results in multiple transcript variants encoding multiple isoforms. [provided by RefSeq, Sep 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO06020 | MIA2 Knockout cell line (HeLa) | Human | MIA2 | 1:3~1:6 | Negative | Online Inquiry |
KO06021 | MIA2 Knockout cell line (HCT 116) | Human | MIA2 | 1:2~1:4 | Negative | Online Inquiry |
KO06022 | MIA2 Knockout cell line (HEK293) | Human | MIA2 | 1:3~1:6 | Negative | Online Inquiry |
KO06023 | MIA2 Knockout cell line (A549) | Human | MIA2 | 1:3~1:4 | Negative | Online Inquiry |
MIA2 Gene Knockout Cell Lines are highly specialized cellular models engineered to facilitate the study of the MIA2 gene, a critical component involved in the regulation of cellular responses to various stimuli, including inflammation and cancer progression. These cell lines have been meticulously developed through the CRISPR-Cas9 genome editing technology, enabling precise alterations to the MIA2 locus, thereby creating a non-functional knockout variant. This advancement not only allows researchers to delineate the gene's specific role but also provides a robust platform for functional assays to explore its implications in disease mechanisms.
The primary function of MIA2 Gene Knockout Cell Lines is to eliminate the expression of the MIA2 gene, thus enabling scientists to observe cellular behavior and signaling pathways devoid of its influence. Such knockout models are invaluable in elucidating the molecular interactions that underpin pathological conditions, as well as in the development of targeted therapeutic strategies. They serve as essential tools for investigating the gene's involvement in cellular processes such as migration, adhesion, and proliferation, making them pivotal in cancer research and regenerative medicine.
Scientifically, MIA2 Gene Knockout Cell Lines contribute significantly to the understanding of cell signaling and gene function, offering insights applicable in both academic and clinical research settings. Their role extends to drug discovery, where screening for therapeutic compounds can be conducted in a controlled environment that accurately mimics disease states.
Compared to traditional models, MIA2 Gene Knockout Cell Lines offer unparalleled specificity and accuracy in gene function studies, reducing experimental variability and enhancing reproducibility in research outcomes. The precision of CRISPR-Cas9 technology ensures that these cell lines can be reliably used in a myriad of applications, transcending the limitations of previous genetic modification techniques.
For researchers and clinicians focused on advancing biomedical science, the value of MIA2 Gene Knockout Cell Lines is clear: they represent a transformative resource for diving deeper into gene functionality and disease pathology. By providing detailed, context-rich insights, these models empower scientists to make informed decisions in their studies and facilitate the translation of findings into clinical applications.
Our company prides itself on delivering high-quality, specifically-engineered biological products that cater to the ever-evolving needs of the research community. With extensive expertise in genome editing technologies and an unwavering commitment to innovation, we provide researchers with the essential tools required to drive scientific discovery and improve patient outcomes.
Please note that all services are for research use only. Not intended for any clinical use.
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