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MGAM Knockout Cell Lines

Gene: MGAM

Official Full Name: maltase-glucoamylaseprovided by HGNC

Gene Summary: This gene encodes maltase-glucoamylase, which is a brush border membrane enzyme that plays a role in the final steps of digestion of starch. The protein has two catalytic sites identical to those of sucrase-isomaltase, but the proteins are only 59% homologous. Both are members of glycosyl hydrolase family 31, which has a variety of substrate specificities. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO33681 MGAM Knockout cell line (A549) Human MGAM 1:3~1:4 Negative Online Inquiry

Background

MGAM Gene Knockout Cell Lines are precision-engineered cell lines that have undergone targeted gene disruption to eliminate the expression of the Maltase-Glucoamylase (MGAM) gene. This product serves as a vital tool for researchers investigating the roles of carbohydrate metabolism and intestinal health. The MGAM protein is key in the digestion of dietary starches, and its absence in these knockout cell lines allows for a deeper exploration of the consequences of impaired carbohydrate absorption and its implications for various metabolic disorders.

The core function of MGAM Gene Knockout Cell Lines lies in their ability to replicate the physiological conditions of MGAM deficiency without the confounding factors present in in vivo models. Researchers utilize these cell lines to elucidate the mechanisms underpinning glucose homeostasis, evaluate the effects of dietary interventions, and test the efficacy of potential therapeutics aimed at modulating glycemic responses. By facilitating high-throughput screening of pharmacological agents and biotherapeutics, these cell lines are instrumental in advancing our understanding of metabolic diseases.

The scientific importance of MGAM Gene Knockout Cell Lines is underscored by their application in both fundamental and applied research settings, including but not limited to metabolic syndrome, diabetes, and gastrointestinal disorders. They provide a unique opportunity to study gene function in a controlled environment, enabling more accurate modeling of human diseases.

What sets our MGAM Gene Knockout Cell Lines apart from competing products is the precision and customizability of gene editing, achieved through state-of-the-art CRISPR-Cas9 technology. Our commitment to quality ensures that each product undergoes rigorous validation to confirm the efficiency of gene knockout and its functional characteristics in biological assays. Moreover, these lines are provided alongside detailed protocols for easy implementation, simplifying the research process.

Researchers, clinicians, and pharmaceutical companies will find value in our MGAM Gene Knockout Cell Lines for their ability to generate reliable and reproducible data that informs both basic research and clinical applications. As a leader in the field of molecular biology products, our company leverages extensive expertise in gene editing techniques, ensuring our offerings meet the highest scientific standards and support innovative research endeavors across various domains.

Please note that all services are for research use only. Not intended for any clinical use.

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