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METTL15 Knockout Cell Lines

Gene: METTL15

Official Full Name: methyltransferase 15, mitochondrial 12S rRNA N4-cytidineprovided by HGNC

Gene Summary: Enables rRNA (cytosine-N4-)-methyltransferase activity. Involved in rRNA base methylation. Is active in mitochondrial matrix. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16224 METTL15 Knockout cell line (HeLa) Human METTL15 1:3~1:6 Negative Online Inquiry
KO16225 METTL15 Knockout cell line (HCT 116) Human METTL15 1:2~1:4 Negative Online Inquiry
KO16226 METTL15 Knockout cell line (HEK293) Human METTL15 1:3~1:6 Negative Online Inquiry
KO16227 METTL15 Knockout cell line (A549) Human METTL15 1:3~1:4 Negative Online Inquiry

Background

METTL15 Gene Knockout Cell Lines are expertly engineered cellular models characterized by the targeted deletion of the METTL15 gene, which encodes a methyltransferase that plays a crucial role in the regulation of RNA modification processes. These cell lines offer a unique platform for understanding the biochemical pathways influenced by METTL15, enabling researchers to dissect its role in various physiological contexts such as cellular differentiation, stress responses, and the modulation of gene expression.

With the ability to effectively manipulate the METTL15 gene, these knockout cell lines facilitate detailed investigations into the metabolic and epigenetic changes that result from the absence of this gene. By employing CRISPR-Cas9 technology for precise gene editing, researchers can ensure stable and reproducible models, which are essential for reliable experimentation. The absence of METTL15 provides insight into its functional relevance, aiding in the elucidation of the molecular mechanisms underlying health and disease states.

The scientific importance of METTL15 Gene Knockout Cell Lines extends into numerous applications, from basic research in gene function to preclinical studies assessing the role of RNA methylation in cancer and autoimmune diseases. Their use can lead to the identification of novel therapeutic targets and biomarkers, thus holding promise for translational research efforts.

What sets these cell lines apart from alternatives is their specificity, efficiency, and the robust validation of gene knockout efficiencies. Unlike traditional methods that may involve more generalized approaches to gene disruption, our METTL15 knockout lines provide precise insights that are essential for targeted research. This unique advantage significantly enhances the reliability of experimental outcomes.

For researchers and clinicians seeking to deepen their understanding of RNA modification and its implications in various biological processes, METTL15 Gene Knockout Cell Lines are an invaluable resource. Our company prides itself on delivering high-quality, innovative biological products, backed by years of expertise and a commitment to advancing scientific discovery. With a focus on enabling accurate and novel research solutions, we strive to support the scientific community's endeavors in unraveling complex biological questions.

Please note that all services are for research use only. Not intended for any clinical use.

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