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MEIS1 Knockout Cell Lines

Gene: MEIS1

Official Full Name: Meis homeobox 1provided by HGNC

Gene Summary: Homeobox genes, of which the most well-characterized category is represented by the HOX genes, play a crucial role in normal development. In addition, several homeoproteins are involved in neoplasia. This gene encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO36671 MEIS1 Knockout cell line (HeLa) Human MEIS1 1:3~1:6 Negative Online Inquiry
KO36672 MEIS1 Knockout cell line (HEK293) Human MEIS1 1:3~1:6 Negative Online Inquiry
KO36673 MEIS1 Knockout cell line (A549) Human MEIS1 1:3~1:4 Negative Online Inquiry

Background

MEIS1 Gene Knockout Cell Lines are highly specialized biological products designed for advanced genetic research. These cell lines have been engineered to lose the function of the MEIS1 gene, a critical regulator involved in various developmental and cellular processes. By specifically disrupting the MEIS1 gene, researchers can investigate its role in hematopoiesis, stem cell function, and other biological pathways, thereby providing a powerful tool for elucidating the underlying mechanisms of diseases such as leukemia and other blood-related disorders.

The primary function of MEIS1 Gene Knockout Cell Lines is to facilitate the study of gene function through the observation of phenotypic changes following MEIS1 disruption. These cell lines utilize CRISPR-Cas9 technology for precise gene editing, allowing for the creation of knockout models that can be subjected to various assays. By analyzing differences in proliferation, differentiation, and signaling pathways between knockout and wild-type cells, researchers can gain critical insights into gene function and its implications in health and disease.

The scientific importance of these cell lines extends to both basic research and translational applications. In research settings, these models aid in investigating gene-environment interactions, epigenetic regulation, and the molecular basis of diseases. Clinically, understanding the role of MEIS1 can enhance therapeutic approaches by identifying novel targets for drug development, ultimately leading to improved treatment strategies for cancer patients.

One notable advantage of MEIS1 Gene Knockout Cell Lines is their rigorous validation and optimization, ensuring reproducibility and reliability in experimental outcomes. Unlike other genetic models, these specifically tailored cell lines offer precise control over the genetic makeup, which is crucial for studies requiring high specificity and consistency.

The value of MEIS1 Gene Knockout Cell Lines lies not only in their innovative approach to gene editing but also in the breadth of applications they support, from basic biology to clinical research. For researchers and clinicians looking to deepen their understanding of pathological processes and develop new therapeutic strategies, these cell lines provide a critical resource.

Our company prides itself on its commitment to advancing biotechnological solutions, leveraging state-of-the-art technologies and expertise in genetic engineering. We are dedicated to equipping researchers with the tools they need to drive innovation and discoveries in the field of molecular biology.

Please note that all services are for research use only. Not intended for any clinical use.

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