Gene: LPIN2
Official Full Name: lipin 2provided by HGNC
Gene Summary: Mouse studies suggest that this gene functions during normal adipose tissue development and may play a role in human triglyceride metabolism. This gene represents a candidate gene for human lipodystrophy, characterized by loss of body fat, fatty liver, hypertriglyceridemia, and insulin resistance. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO09143 | LPIN2 Knockout cell line (HeLa) | Human | LPIN2 | 1:3~1:6 | Negative | Online Inquiry |
KO09144 | LPIN2 Knockout cell line (HCT 116) | Human | LPIN2 | 1:2~1:4 | Negative | Online Inquiry |
KO09145 | LPIN2 Knockout cell line (HEK293) | Human | LPIN2 | 1:3~1:6 | Negative | Online Inquiry |
KO09146 | LPIN2 Knockout cell line (A549) | Human | LPIN2 | 1:3~1:4 | Negative | Online Inquiry |
LPIN2 Gene Knockout Cell Lines are meticulously developed cellular models designed to investigate the roles of the LPIN2 gene, known for its involvement in lipid metabolism and cellular signaling pathways. These cell lines are engineered through precise gene-editing technologies, enabling the complete knockout of the LPIN2 gene, leading to a profound understanding of its biological functions and implications in metabolic disorders.
The key mechanism of these knockout cell lines involves the selective disruption of the LPIN2 gene, resulting in the cessation of its protein product expression. This allows researchers to observe resultant phenotypic changes in cellular processes such as lipid synthesis, energy metabolism, and cell growth regulation. By utilizing these models, scientists can delineate the impact of LPIN2 deficiency on metabolic pathways and disease states such as obesity, diabetes, and cardiovascular conditions.
In scientific research and clinical applications, LPIN2 Gene Knockout Cell Lines provide invaluable insights into the molecular mechanisms underlying lipid homeostasis and metabolic regulation. Their use extends beyond basic research, holding potential implications for therapeutic strategies targeting metabolic diseases. Understanding LPIN2's role offers pathways for developing interventions to mitigate these conditions, making them relevant for researchers and clinicians alike.
What sets our LPIN2 Gene Knockout Cell Lines apart from alternatives is our commitment to quality and reproducibility. Our products undergo rigorous validations to ensure consistent performance across different experimental setups. Furthermore, we offer comprehensive technical support and guidance, maximizing the potential for groundbreaking research outcomes.
In conclusion, our LPIN2 Gene Knockout Cell Lines represent a pivotal resource for those aiming to unravel the complexities of lipid metabolism and related pathologies. Backed by our extensive expertise in genetic engineering and cell line development, we are dedicated to enhancing research capabilities in the biomedical field, empowering researchers and clinicians with the tools they need to advance scientific knowledge and therapeutic solutions.
Please note that all services are for research use only. Not intended for any clinical use.
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