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LHFPL6 Knockout Cell Lines

Gene: LHFPL6

Official Full Name: LHFPL tetraspan subfamily member 6provided by HGNC

Gene Summary: This gene is a member of the lipoma HMGIC fusion partner (LHFP) gene family, which is a subset of the superfamily of tetraspan transmembrane protein encoding genes. This gene is fused to a high-mobility group gene in a translocation-associated lipoma. Mutations in another LHFP-like gene result in deafness in humans and mice. Alternatively spliced transcript variants have been found; however, their full-length nature is not known. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32178 LHFPL6 Knockout cell line (HeLa) Human LHFPL6 1:3~1:6 Negative Online Inquiry
KO32179 LHFPL6 Knockout cell line (HEK293) Human LHFPL6 1:3~1:6 Negative Online Inquiry
KO32180 LHFPL6 Knockout cell line (A549) Human LHFPL6 1:3~1:4 Negative Online Inquiry

Background

LHFPL6 Gene Knockout Cell Lines are specifically engineered cellular models that possess a targeted disruption of the LHFPL6 gene, a gene associated with various physiological processes. By utilizing state-of-the-art CRISPR/Cas9 gene-editing technology, these cell lines provide researchers with a powerful tool to investigate the functional role of LHFPL6 in cellular pathways and disease mechanisms. The knockout of this gene facilitates the study of its contribution to processes such as cell differentiation, signaling pathways, and potential impacts on disease states, particularly in neurobiological contexts.

Mechanistically, the LHFPL6 Gene Knockout Cell Lines allow for the examination of the absence of LHFPL6 and its downstream effects within the cellular milieu. Researchers can apply these models to assess changes in phenotypic characteristics, gene expression profiles, and proteomic shifts that occur due to the loss of LHFPL6 function. This enables a more comprehensive understanding of how this gene contributes to various biological phenomena, both under normal conditions and in pathophysiological contexts.

The scientific importance of LHFPL6 Gene Knockout Cell Lines extends to their wide range of applications in both basic research and translational science. These cell lines are invaluable for drug discovery processes, genetic studies, and the development of new therapeutic strategies. By providing a detailed understanding of the gene's molecular pathways, they can help identify potential targets for new treatments, thereby advancing clinical applications.

Compared to alternative models, the LHFPL6 Gene Knockout Cell Lines present distinct advantages, including high specificity and reproducibility in genetic disruption. They facilitate efficient screening and provide robust data that improves experimental integrity. Additionally, the established gene editing technology ensures a consistent knockout efficiency, thereby reducing variability seen in traditional genetic manipulation techniques.

For researchers and clinicians, the value of LHFPL6 Gene Knockout Cell Lines lies in their ability to accelerate the understanding of gene function and pathology in a controlled environment, ultimately leading to enhanced insights that can culminate in innovative treatment approaches.

Our company is committed to delivering high-quality biological tools, and our expertise in genetic engineering and cell line development positions us as a reliable partner in advancing scientific research and applications. We strive to empower scientists with precise and effective solutions that drive discoveries in molecular and cellular biology.

Please note that all services are for research use only. Not intended for any clinical use.

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