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LGALS1 Knockout Cell Lines

Gene: LGALS1

Official Full Name: galectin 1provided by HGNC

Gene Summary: The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. This gene product may act as an autocrine negative growth factor that regulates cell proliferation. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO06285 LGALS1 Knockout cell line (HeLa) Human LGALS1 1:3~1:6 Negative Online Inquiry
KO06286 LGALS1 Knockout cell line (HCT 116) Human LGALS1 1:2~1:4 Negative Online Inquiry
KO06287 LGALS1 Knockout cell line (HEK293) Human LGALS1 1:3~1:6 Negative Online Inquiry
KO06288 LGALS1 Knockout cell line (A549) Human LGALS1 1:3~1:4 Negative Online Inquiry

Background

LGALS1 Gene Knockout Cell Lines are genetically engineered cellular models designed to lack the expression of the LGALS1 gene, which encodes the galectin-1 protein. Galectin-1 is a β-galactoside-binding lectin implicated in diverse biological processes, including cell differentiation, proliferation, and immune regulation. These knockout cell lines serve as invaluable tools for researchers investigating the multifaceted roles of galectin-1 in both physiological and pathological conditions.

The primary function of LGALS1 knockout cell lines lies in their ability to elucidate the molecular mechanisms through which galectin-1 influences cellular behavior. By studying the differential expression of genes and proteins in the absence of LGALS1, researchers can gain insight into its role in processes such as tumor progression, inflammation, and immune response modulation. This provides critical data for understanding diseases where galectin-1 is thought to play a key role, including cancer, autoimmune diseases, and infectious diseases.

Scientifically, these cell lines are significant as they can serve as a basis for drug discovery efforts, allowing for the identification of compounds that may target galectin-1-related pathways. In clinical settings, understanding the role of galectin-1 can potentially lead to novel therapeutic strategies for conditions such as cancer, where galectin-1 is often overexpressed and associated with poor prognosis.

Compared to alternatives, the advantages of LGALS1 gene knockout cell lines include their specificity and reliability. These knockout lines eliminate confounding factors associated with partial inhibition or overexpression of the target gene, allowing for more precise assessments of galectin-1 functions. Additionally, they can be generated in various cell types, enabling tailored experiments based on the specific needs of the researcher.

In conclusion, LGALS1 Gene Knockout Cell Lines are essential resources for any researcher or clinician looking to delve into the complexities of galectin-1 biology and its implications in health and disease. Our company is dedicated to providing high-quality biological products and is backed by extensive expertise in genetic engineering, ensuring that you receive reliable and innovative tools for your research needs.

Please note that all services are for research use only. Not intended for any clinical use.

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