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LECT2 Knockout Cell Lines

Gene: LECT2

Official Full Name: leukocyte cell derived chemotaxin 2provided by HGNC

Gene Summary: This gene encodes a secreted, 16 kDa protein that acts as a chemotactic factor to neutrophils and stimulates the growth of chondrocytes and osteoblasts. This protein has high sequence similarity to the chondromodulin repeat regions of the chicken myb-induced myeloid 1 protein. A polymorphism in this gene may be associated with rheumatoid arthritis. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO36846 LECT2 Knockout cell line (HEK293) Human LECT2 1:3~1:6 Negative Online Inquiry

Background

LECT2 Gene Knockout Cell Lines are specialized biological tools developed to facilitate the in-depth investigation of the LECT2 gene and its associated pathways. These cell lines have undergone precise genetic modification through the CRISPR-Cas9 gene-editing technology, resulting in the complete knockout of the LECT2 gene. As a result, they serve as an invaluable resource for researchers aiming to explore the physiological and pathological roles of LECT2, a gene implicated in various human diseases, including inflammatory conditions and metabolic syndromes.

The primary function of LECT2 gene knockout cell lines lies in their ability to mimic a LECT2-deficient state in vitro, allowing for detailed studies of gene function and interaction networks. By leveraging these cell lines, researchers can delve into the molecular mechanisms by which LECT2 influences cellular processes, such as immune response modulation and lipid metabolism. The absence of LECT2 also enables deeper investigations into its potential as a biomarker or therapeutic target, providing insights that could translate into novel therapeutic strategies.

The scientific significance of these knockout cell lines extends into diverse research fields, from immunology to cancer biology. Their applications in preclinical studies enable assays for drug discovery and validation, making them essential tools in both academic and pharmaceutical research settings. Furthermore, compared to alternatives, such as wild-type cell lines or partial gene knockdowns, our LECT2 knockout cell lines offer a complete loss-of-function model, ensuring higher accuracy and relevance in experimental outcomes.

For researchers and clinicians, the value of LECT2 gene knockout cell lines is amplified by their ability to accelerate hypotheses testing and enhance the reproducibility of results, ultimately expediting the translation of basic research into clinical applications. The clear advantage of utilizing well-characterized and validated cell lines fosters clinical relevance and directs pathways for targeted therapeutic development.

Our company is dedicated to advancing biomedical research through innovative biological products. With extensive expertise in genetic engineering and cell line development, we pride ourselves on providing high-quality resources that empower researchers to drive forward their scientific inquiries with reliability and precision.

Please note that all services are for research use only. Not intended for any clinical use.

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