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LDOC1 Knockout Cell Lines

Gene: LDOC1

Official Full Name: LDOC1 regulator of NFKB signalingprovided by HGNC

Gene Summary: The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29026 LDOC1 Knockout cell line (HeLa) Human LDOC1 1:3~1:6 Negative Online Inquiry
KO29027 LDOC1 Knockout cell line (HEK293) Human LDOC1 1:3~1:6 Negative Online Inquiry
KO29028 LDOC1 Knockout cell line (A549) Human LDOC1 1:3~1:4 Negative Online Inquiry

Background

LDOC1 Gene Knockout Cell Lines represent a cutting-edge addition to the realm of genetic research, specifically designed to facilitate the study of the LDOC1 gene's role in various biological processes. These cell lines have been meticulously engineered using CRISPR-Cas9 technology to create precise knockout models, which provide a powerful tool for dissecting gene function and its contributions to cellular pathways involved in development, disease, and apoptosis.

The primary function of these knockout cell lines lies in their ability to allow researchers to observe the phenotypic changes that occur in the absence of LDOC1, thereby elucidating its molecular mechanisms. By studying the cells' response to various stimuli and stress conditions, scientists can gain insights into how LDOC1 influences processes such as immune response, tumorigenesis, and neurodevelopment. The resultant data are vital for advancing our understanding of numerous health conditions, including cancer and neurodegenerative diseases.

In research and clinical settings, LDOC1 knockout cell lines offer significant advantages over traditional methods, such as overexpression or knockdown strategies with siRNA. They generate more robust and reproducible data, as they create a truly defined genetic background without residual expression of the target gene. This precision is critical, as it mitigates off-target effects that could confound experimental results, allowing for clearer interpretations of gene function.

The unique selling points of LDOC1 Gene Knockout Cell Lines include their high specificity, user-friendly protocols for implementation, and compatibility with a wide range of experimental assays, including drug screening and molecular interaction studies. By investing in this product, researchers and clinicians can accelerate their studies, leading to novel discoveries that enhance our understanding of biological systems and inform future therapeutic strategies.

Our commitment to excellence in biological research is underscored by our experienced team and our dedication to providing high-quality, innovative products that meet the evolving needs of the scientific community. With LDOC1 Gene Knockout Cell Lines in their toolkit, researchers will be well-equipped to advance inquiries into the functional roles of this important gene.

Please note that all services are for research use only. Not intended for any clinical use.

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