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LCORL Knockout Cell Lines

Gene: LCORL

Official Full Name: ligand dependent nuclear receptor corepressor likeprovided by HGNC

Gene Summary: This gene encodes a transcription factor that appears to function in spermatogenesis. Polymorphisms in this gene are associated with measures of skeletal frame size and adult height. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO05584 LCORL Knockout cell line (HeLa) Human LCORL 1:3~1:6 Negative Online Inquiry
KO05585 LCORL Knockout cell line (HCT 116) Human LCORL 1:2~1:4 Negative Online Inquiry
KO05586 LCORL Knockout cell line (HEK293) Human LCORL 1:3~1:6 Negative Online Inquiry
KO05587 LCORL Knockout cell line (A549) Human LCORL 1:3~1:4 Negative Online Inquiry

Background

LCORL Gene Knockout Cell Lines are specialized cellular models designed to allow researchers to study the functional consequences of the loss of the LCORL gene, associated with various physiological and pathological processes. This product is generated through advanced CRISPR-Cas9 gene-editing technology, ensuring precise and efficient disruption of the LCORL gene, resulting in knockout cell lines that facilitate extensive study into gene function, signaling pathways, and disease mechanisms.

The key mechanisms of these cell lines rest on their ability to mimic disease states by enabling scientists to investigate how the absence of LCORL affects cellular behavior, including proliferation, differentiation, and signal transduction. By providing a controlled environment where gene expression can be monitored, these models are vital for elucidating the biological roles of LCORL, particularly in relation to associated disorders such as cancer and metabolic diseases.

In research and clinical settings, LCORL Gene Knockout Cell Lines serve as crucial tools for drug discovery and validation, potentially leading to the identification of novel therapeutic targets. Their use in functional genomics allows for hypothesis-driven research into gene interactions and the pathways related to LCORL, thereby accelerating the translation of fundamental biology into clinical practice.

Compared to alternative models, LCORL knockouts offer enhanced specificity and reproducibility, reducing the risk of off-target effects often observed with less sophisticated methods. This specificity guarantees more reliable data, giving researchers an invaluable asset in the quest for understanding gene function and its implications in health and disease.

For scientists delving into the complexities of gene function, these knockout cell lines are indispensable. They not only provide insights that could lead to breakthroughs in therapeutic approaches but also empower researchers to explore innovative methodologies in system biology.

At our company, we pride ourselves in delivering high-quality biological products that are informed by leading-edge science and a commitment to supporting researchers in their pursuit of groundbreaking discoveries. Our expertise in gene editing technologies ensures that our offerings meet the highest standards of reliability and utility, positioning us as a trusted partner in the life sciences field.

Please note that all services are for research use only. Not intended for any clinical use.

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