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LCN12 Knockout Cell Lines

Gene: LCN12

Official Full Name: lipocalin 12provided by HGNC

Gene Summary: Members of the lipocalin family, such as LCN12, have a common structure consisting of an 8-stranded antiparallel beta-barrel that forms a cup-shaped ligand-binding pocket or calyx. Lipocalins generally bind small hydrophobic ligands and transport them to specific cells (Suzuki et al., 2004 [PubMed 15363845]).[supplied by OMIM, Aug 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16587 LCN12 Knockout cell line (HeLa) Human LCN12 1:3~1:6 Negative Online Inquiry

Background

LCN12 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to facilitate the study of the LCN12 gene's functions in various biological contexts. By employing CRISPR-Cas9 technology, these cell lines exhibit complete ablation of the LCN12 gene, providing researchers with a powerful tool to investigate its role in cellular processes, disease pathways, and potential therapeutic targets.

The primary function of LCN12 Gene Knockout Cell Lines is to enable the study of gene function through loss-of-function analyses. By removing the LCN12 gene expression, researchers can elucidate its involvement in key biological mechanisms such as lipid metabolism, immune responses, and inflammation. The resulting phenotypic changes observed in these knockout cells can offer significant insights into the molecular underpinnings of various physiological and pathological conditions.

The scientific importance of LCN12 Gene Knockout Cell Lines lies in their versatile applications. They serve as essential models in both basic research and clinical settings, including drug development, biomarker identification, and the exploration of gene therapy approaches. Moreover, understanding the role of LCN12 in specific diseases can lead to the identification of novel therapeutic strategies, enhancing patient outcomes.

Compared to alternative models, such as transient knockdown systems or conventional knockout organisms, LCN12 Gene Knockout Cell Lines provide greater stability and reproducibility. These cell lines bypass the variability associated with transient transfections and offer the advantage of consistent gene expression profiles over extended periods, allowing for more robust experimental designs.

For researchers and clinicians invested in gene function studies, the value of LCN12 Gene Knockout Cell Lines cannot be overstated. They facilitate high-throughput screening, contribute to the discovery of gene-disease associations, and translate findings into potential clinical applications. Equipped with a deep understanding of genetic manipulation, our company is committed to providing cutting-edge biological tools that empower science and drive innovation forward.

Please note that all services are for research use only. Not intended for any clinical use.

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