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LAPTM4B Knockout Cell Lines

Gene: LAPTM4B

Official Full Name: lysosomal protein transmembrane 4 betaprovided by HGNC

Gene Summary: Enables ceramide binding activity; enzyme binding activity; and phosphatidylinositol bisphosphate binding activity. Involved in several processes, including endosome transport via multivesicular body sorting pathway; negative regulation of macromolecule metabolic process; and regulation of lysosomal membrane permeability. Located in several cellular components, including endosome; lysosomal membrane; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00338 LAPTM4B Knockout cell line (HeLa) Human LAPTM4B 1:3~1:6 Negative Online Inquiry
KO20635 LAPTM4B Knockout cell line (HCT 116) Human LAPTM4B 1:2~1:4 Negative Online Inquiry
KO20636 LAPTM4B Knockout cell line (HEK293) Human LAPTM4B 1:3~1:6 Negative Online Inquiry
KO20637 LAPTM4B Knockout cell line (A549) Human LAPTM4B 1:3~1:4 Negative Online Inquiry

Background

LAPTM4B Gene Knockout Cell Lines are specialized cellular models engineered to specifically disrupt the LAPTM4B gene, which encodes a lysosomal protein implicated in various biological processes, including cellular trafficking and signal transduction. These cell lines serve as invaluable tools for researchers aiming to elucidate the functional role of LAPTM4B in cellular physiology, pathology, and its potential involvement in oncogenesis. By creating a knockout of this gene, researchers can rigorously assess the phenotypic and molecular changes that result from its absence, leading to a deeper understanding of its biological significance.

The mechanisms underlying the functions of LAPTM4B are diverse, involving interactions with cellular pathways that regulate cellular homeostasis and response to environmental stressors. By studying these knockout cell lines, scientists can explore how LAPTM4B influences lysosomal function, autophagy, and signaling pathways that may contribute to disease processes such as cancer or neurodegeneration. This mechanistic analysis is vital for developing targeted therapeutic strategies.

In a research context, LAPTM4B Gene Knockout Cell Lines provide a controlled environment to investigate molecular interactions and assess drug responses, enabling the identification of novel biomarkers or therapeutic targets. Clinicians can leverage findings from studies using these cell lines to enhance patient outcomes by tailoring therapeutic regimens based on LAPTM4B-related pathways.

One key advantage of LAPTM4B Gene Knockout Cell Lines is their specificity and reliability compared to alternative methods such as RNA interference or CRISPR interference. These cell lines ensure a stable and complete loss of gene function, which can be crucial for reproducibility and accuracy in experimental outcomes. This specificity reduces off-target effects and allows for a more straightforward interpretation of results.

For researchers and clinicians aiming to advance their work in gene function, cellular mechanisms, or disease models, LAPTM4B Gene Knockout Cell Lines represent an indispensable asset. Their design facilitates groundbreaking research, contributing to the scientific community's collective understanding of gene functions and their clinical implications.

Our company prides itself on its deep expertise in producing high-quality biological products, including state-of-the-art knockout cell lines. We are committed to empowering researchers with the tools they need to push the boundaries of science and medicine.

Please note that all services are for research use only. Not intended for any clinical use.

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