Gene: LANCL2
Official Full Name: LanC like glutathione S-transferase 2provided by HGNC
Gene Summary: Enables phosphatidylinositol-3-phosphate binding activity; phosphatidylinositol-4-phosphate binding activity; and phosphatidylinositol-5-phosphate binding activity. Involved in negative regulation of DNA-templated transcription and positive regulation of abscisic acid-activated signaling pathway. Located in several cellular components, including cortical actin cytoskeleton; cytosol; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO16605 | LANCL2 Knockout cell line (HeLa) | Human | LANCL2 | 1:3~1:6 | Negative | Online Inquiry |
KO16606 | LANCL2 Knockout cell line (HCT 116) | Human | LANCL2 | 1:2~1:4 | Negative | Online Inquiry |
KO16607 | LANCL2 Knockout cell line (HEK293) | Human | LANCL2 | 1:3~1:6 | Negative | Online Inquiry |
KO16608 | LANCL2 Knockout cell line (A549) | Human | LANCL2 | 1:3~1:4 | Negative | Online Inquiry |
LANCL2 Gene Knockout Cell Lines are engineered cellular models that specifically lack the expression of the LANCL2 gene, which is known for its involvement in various physiological processes, including metabolism and cell signaling. By utilizing CRISPR-Cas9 gene editing technology, these cell lines provide researchers with a robust tool for studying gene function, elucidating pathways and networks involved in disease mechanisms, and evaluating potential therapeutic targets.
The primary function of LANCL2 Gene Knockout Cell Lines is to facilitate the investigation of the role of LANCL2 in cellular behavior and response to various stimuli. By comparing these knockout models to wild-type counterparts, scientists can dissect the contributions of LANCL2 to crucial processes such as insulin signaling, apoptosis, and inflammation. The absence of LANCL2 enables clear insights into impaired cellular functions and can help to identify downstream signaling cascades that may be crucial for understanding metabolic disorders or cancer.
The scientific importance of these knockout cell lines lies in their applicability across a diverse range of research fields, particularly in metabolic research, drug development, and cancer biology. In clinical settings, these cell lines allow for the exploration of therapeutic interventions directed at LANCL2-related pathways, potentially leading to novel strategies for managing diseases.
Compared to traditional cell lines, which often suffer from background noise due to varying expression levels of target genes, LANCL2 Gene Knockout Cell Lines offer a clean genetic background that enhances the reliability and reproducibility of experimental results. This specificity makes them invaluable for researchers seeking to untangle complex cellular pathways without the confounding factors present in non-targeted models.
For researchers and clinicians, the ability to utilize a precise tool for understanding the biology of LANCL2 represents a significant step forward in the quest to decipher intricate biological mechanisms. Moreover, these specialized cell lines underscore our company's dedication to providing innovative solutions that enhance scientific discovery. Our expertise in genetic engineering and commitment to quality ensure that LANCL2 Gene Knockout Cell Lines are a dependable resource for advancing research and potential therapeutic development.
Please note that all services are for research use only. Not intended for any clinical use.
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