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KRTAP21-2 Knockout Cell Lines

Gene: KRTAP21-2

Official Full Name: keratin associated protein 21-2provided by HGNC

Gene Summary: Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16621 KRTAP21-2 Knockout cell line (HEK293) Human KRTAP21-2 1:3~1:6 Negative Online Inquiry

Background

KRTAP21-2 Gene Knockout Cell Lines are genetically modified cell lines with a targeted deletion of the keratin-associated protein 21-2 (KRTAP21-2) gene, which is primarily involved in the regulation of keratin filament formation in epithelial tissues. These cell lines serve as essential tools for understanding the role of KRTAP21-2 in various physiological and pathological processes, including skin development, hair follicle biology, and fibrotic conditions.

The primary function of these knockout cell lines is to facilitate the dissection of the biological pathways influenced by KRTAP21-2. By observing cellular behaviors such as proliferation, apoptosis, and differentiation in the absence of this gene, researchers can elucidate mechanisms related to keratinization and tissue integrity. These insights have significant implications for understanding dermatological diseases and potential therapeutic targets.

Scientifically, KRTAP21-2 Gene Knockout Cell Lines are invaluable in both research and clinical environments. They enable detailed investigations into the molecular underpinnings of skin disorders, offering a platform for drug discovery and efficacy testing. Furthermore, their application extends to exploring the mechanisms of hair loss and the development of innovative treatments for alopecia and related conditions.

Compared to alternative models, such as wild-type cell lines or less specific knockout models, these KRTAP21-2 knockout lines offer precision and specificity in targeting keratin-associated functions, making them superior for studies focused on keratin-related biology. Their ability to mimic the physiological conditions of human tissues gives researchers a reliable system in which to conduct experiments.

For researchers and clinicians, the KRTAP21-2 Gene Knockout Cell Lines are not just another tool; they are a transformative asset that can significantly advance studies on keratin-related disorders and pave the way for novel therapeutic strategies. Our company, with extensive expertise in genetic engineering and a commitment to providing high-quality biological products, ensures that these cell lines meet rigorous scientific standards to empower your research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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