Gene: KLHL28
Official Full Name: kelch like family member 28provided by HGNC
Gene Summary: Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of Cul3-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO16655 | KLHL28 Knockout cell line (HeLa) | Human | KLHL28 | 1:3~1:6 | Negative | Online Inquiry |
KO16656 | KLHL28 Knockout cell line (HCT 116) | Human | KLHL28 | 1:2~1:4 | Negative | Online Inquiry |
KO16657 | KLHL28 Knockout cell line (HEK293) | Human | KLHL28 | 1:3~1:6 | Negative | Online Inquiry |
KO16658 | KLHL28 Knockout cell line (A549) | Human | KLHL28 | 1:3~1:4 | Negative | Online Inquiry |
KLHL28 Gene Knockout Cell Lines are a sophisticated biological tool designed to facilitate the study of the KLHL28 gene, which is involved in various cellular processes, including protein degradation and cellular signaling pathways. These cell lines are created by employing CRISPR-Cas9 technology to disrupt the KLHL28 gene, enabling researchers to observe the effects of this knockout on cellular functions and to investigate the gene's role in disease mechanisms.
The key function of KLHL28 Gene Knockout Cell Lines lies in their ability to provide a model for understanding the physiological effects of KLHL28 deficiency. By studying these cell lines, scientists can explore the protein interactions and downstream signaling cascades influenced by KLHL28, enhancing our understanding of cellular homeostasis and potential dysregulation in disease states. This cellular model is invaluable for elucidating the gene's contribution to pathophysiological conditions, such as cancer and neurodegenerative diseases, where KLHL28's role may be pivotal.
The scientific importance of these cell lines extends to both research and clinical applications. In laboratory settings, they serve as a platform for drug discovery and testing, permitting the examination of therapeutic compounds that target pathways disrupted by KLHL28 mutations. Moreover, they can be utilized in functional genomics studies to assess gene function and interaction networks comprehensively.
Compared to alternative models such as wild-type cell lines or animal models, KLHL28 Gene Knockout Cell Lines provide a simplified and controlled environment that isolates the effects of the KLHL28 gene, thus enhancing the consistency and accuracy of experimental results. This targeted approach minimizes background variability, facilitating clearer interpretations of molecular interactions.
Researchers and clinicians will find these cell lines particularly valuable, as they can accelerate the pace of discovery in understanding genetic contributions to complex diseases and guide the development of novel therapeutic strategies. The specificity of the KLHL28 knockout models allows for more intentional research designs and clearer mechanistic insights.
Our company specializes in the development of high-quality biological products tailored to the needs of the scientific community. We pride ourselves on delivering innovative solutions that empower researchers and drive breakthroughs in genetic research and therapeutic advancements. By choosing KLHL28 Gene Knockout Cell Lines, you are investing in a product that stands at the forefront of genomic research innovation.
Please note that all services are for research use only. Not intended for any clinical use.
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