Gene: KLHL21
Official Full Name: kelch like family member 21provided by HGNC
Gene Summary: Enables cullin family protein binding activity. Contributes to ubiquitin-protein transferase activity. Involved in chromosome passenger complex localization to spindle midzone; protein ubiquitination; and regulation of cytokinesis. Located in polar microtubule. Part of Cul3-RING ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO32547 | KLHL21 Knockout cell line (HeLa) | Human | KLHL21 | 1:3~1:6 | Negative | Online Inquiry |
KO32548 | KLHL21 Knockout cell line (HCT 116) | Human | KLHL21 | 1:2~1:4 | Negative | Online Inquiry |
KO32549 | KLHL21 Knockout cell line (HEK293) | Human | KLHL21 | 1:3~1:6 | Negative | Online Inquiry |
KO32550 | KLHL21 Knockout cell line (A549) | Human | KLHL21 | 1:3~1:4 | Negative | Online Inquiry |
KLHL21 Gene Knockout Cell Lines represent a novel tool for investigating the biological functions and pathways regulated by the KLHL21 gene, which encodes a member of the Kelch-like protein family involved in proteasome-mediated degradation and cellular signaling processes. These cell lines have been precisely engineered to disrupt the KLHL21 gene via CRISPR-Cas9 technology, enabling researchers to study the gene's role in various cellular contexts, including cell cycle regulation, protein homeostasis, and stress response mechanisms.
The primary function of KLHL21 Gene Knockout Cell Lines lies in their ability to elucidate the molecular underpinnings associated with KLHL21-related pathologies, including neurodegenerative diseases and certain cancers. By utilizing these cell lines in functional assays, researchers can manipulate and observe cellular responses to KLHL21 knockout, thereby understanding its role in disease progression or therapeutic resilience. The applicability in research is broad-ranging, with potential experiments designed to explore gene-environment interactions, drug responses, and effective patient stratification in clinical settings.
What sets KLHL21 Gene Knockout Cell Lines apart from alternative products is their precision and ease of use; they are fully characterized, validated, and ready for immediate experimentation. Additionally, the knockouts are generated under stringent quality controls, ensuring reproducibility and reliability across various research applications. This product empowers researchers and clinicians to generate data with higher accuracy while saving time and resources, keys to advancing scientific discovery.
Incorporating KLHL21 Gene Knockout Cell Lines into research could significantly enhance the understanding of gene function and regulation, translating into better therapeutic targets and intervention strategies. With a robust foundation in genetic engineering and a commitment to advancing biotechnological solutions, our company is dedicated to providing leading-edge products that support groundbreaking research in molecular biology and medicine.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.