Gene: KLF15
Official Full Name: KLF transcription factor 15provided by HGNC
Gene Summary: Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of peptidyl-lysine acetylation and positive regulation of transcription by RNA polymerase II. Located in nuclear speck. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO27226 | KLF15 Knockout cell line (HEK293) | Human | KLF15 | 1:3~1:6 | Negative | Online Inquiry |
KLF15 Gene Knockout Cell Lines are genetically engineered cellular models that lack the Krüppel-like factor 15 (KLF15) gene, a pivotal transcription factor involved in various physiological processes including metabolism, cell differentiation, and stress responses. These cell lines are generated through cutting-edge CRISPR/Cas9 technology, ensuring precise and efficient gene editing to facilitate the study of KLF15’s functions in a controlled environment.
The primary mechanism of these KLF15 knockout cell lines involves a significant disruption of KLF15 expression, allowing researchers to investigate the gene's role in cellular processes such as adipogenesis, skeletal muscle development, and organogenesis. By using these knockout lines, scientists can elucidate the pathways KLF15 regulates, enabling a deeper understanding of metabolic disorders and potential therapeutic targets for conditions like diabetes and cardiovascular disease.
In research and clinical settings, KLF15 Gene Knockout Cell Lines serve as invaluable tools to unravel the complexities of gene function and the molecular mechanisms underlying various diseases. Their application extends to drug discovery and the development of gene therapy strategies, where understanding the precise role of KLF15 can lead to targeted interventions.
What sets our KLF15 Gene Knockout Cell Lines apart from other models is their high fidelity and reproducibility, which have been rigorously validated in multiple experiments. Additionally, their availability in various cell types allows researchers to select the most relevant model for their studies, ensuring versatility in experimental design.
For researchers and clinicians, the value of these cell lines lies not only in their robustness but also in their contribution to advancing knowledge in molecular biology and translational research. Our company stands at the forefront of biological product development, committed to providing high-quality genomic resources, including KLF15 Gene Knockout Cell Lines, designed to empower scientists in their quest for innovative solutions to complex biological questions.
Please note that all services are for research use only. Not intended for any clinical use.
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