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IRX6 Knockout Cell Lines

Gene: IRX6

Official Full Name: iroquois homeobox 6provided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription repressor activity, RNA polymerase II-specific; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell development; neuron differentiation; and regulation of DNA-templated transcription. Predicted to act upstream of or within detection of visible light; negative regulation of DNA-templated transcription; and retina morphogenesis in camera-type eye. Predicted to be located in chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16882 IRX6 Knockout cell line (HEK293) Human IRX6 1:3~1:6 Negative Online Inquiry

Background

IRX6 Gene Knockout Cell Lines are specialized cellular models engineered to facilitate the comprehensive study of the IRX6 gene's functions and its roles in biological processes. This product consists of genetically modified cell lines in which the IRX6 gene has been disrupted, thus allowing researchers to observe the resultant phenotypic and molecular changes. The knockout of the IRX6 gene, known for its involvement in developmental processes and potential implications in various pathologies, grants a powerful tool for dissecting the gene's contributions to cellular differentiation, growth regulation, and disease mechanisms.

The key function of IRX6 Gene Knockout Cell Lines lies in their ability to provide insights into the molecular pathways influenced by the IRX6 gene. By eliminating this gene, researchers can analyze downstream effects on signaling pathways, gene expression profiles, and cellular functions. This manipulation helps to elucidate the gene's regulatory roles, which can be pivotal in understanding diseases such as congenital malformations or cancers where IRX6 may play a significant role.

Scientifically, these knockout cell lines have valuable applications in both research and clinical settings. Researchers can employ these models for drug screening, pathway analysis, and functional studies aimed at elucidating the pathogenesis of diseases linked to IRX6 dysregulation. These cell lines also provide an essential resource for developing targeted therapies or diagnostics based on the insights gained from studying IRX6's role in various biological contexts.

Compared to alternative genetic models, the IRX6 Gene Knockout Cell Lines offer unparalleled specificity and versatility. They circumvent the potential off-target effects associated with traditional knockdown techniques (such as siRNA), allowing for more precise investigations. This specificity fosters greater confidence in the reproducibility and reliability of experimental results, critical factors for researchers seeking to publish or develop new applications.

This product is invaluable for researchers and clinicians dedicated to advancing their understanding of genetic foundations in health and disease. By utilizing IRX6 Gene Knockout Cell Lines, scientists can accelerate their research with a strong focus on one of the pivotal genes involved in developmental biology and pathology.

In conclusion, our company brings forth a wealth of experience in genetic engineering and cell line development, ensuring that our IRX6 Gene Knockout Cell Lines are of the highest quality and support your groundbreaking research endeavors in an increasingly competitive biological landscape.

Please note that all services are for research use only. Not intended for any clinical use.

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